The enterprise-grade polysaccharides extraction machine from Xi'an Bioland Instrument Co., Ltd. is designed to get the most beneficial compounds back. Our system gets up to 500% higher extraction rates than other ways, and it only takes 24 to 40 minutes to finish a full processing cycle. Ultrasonic-Assisted Extraction (UAE) technology and low-temperature processing (40–60°C) are combined in this specialty tools to protect beta-glucans and proteoglycans that are sensitive to heat. Our product meets GMP/FDA compliance standards because it has 316L stainless steel touch areas and is controlled by a PLC. The flexible design includes dual-condenser systems that can recover 90–95% of the solvent, explosion-proof setups for handling organic solvents, and the option to include CIP cleaning. This gives pharmaceutical, nutraceutical, and functional food makers complete solutions.
15+ Years of Bioprocessing Expertise
We do more than just sell tools. You get a committed partner who has worked with extraction methods for more than 15 years. Our in-house R&D team is made up of engineers who have worked in production before.
Unmatched Extraction Performance
How efficiently you make things matters. The yields from our systems are 50–500% higher than those from standard ways. The dual-ultrasonic setup successfully breaks down cell walls while vacuum low-temperature processes keeps the active ingredients safe.
Complete Quality Assurance
You deserve to be at ease. Each product has been approved by CE and ISO. We offer full quality warranties that cover one year and include lifetime help for upkeep, so your investment is always safe.
True Customization Capability
Your method is different. We provide real OEM/ODM services and can build a production line that fits your needs. We can change the material specs, tank sizes, and levels of automation to fit your exact needs, whether you're extracting from sea algae or medical mushrooms.
Transparent Production Tracking
During production, you stay updated. Our team sends photos and movies every week to show how things are going. You can either plan a Factory Acceptance Test at our Xi'an facility or get full paperwork to sign off on before the shipment.
End-to-End Support
After buying something, you're never alone. We plan workshops, set up tools, give professional training, and offer quick service after the sale. Our technology experts are still ready to help with troubleshooting and improvement.
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Technology parameter |
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Model |
BL-TN-C50L |
BL-TN -C100L |
BL-TN -C200L |
BL-TN -C300L |
BL-TN -C500L |
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Volume (L) |
50 |
100 |
200 |
300 |
500 |
|
Evaporation capacity (kg/h) |
20 |
50 |
70 |
100 |
200 |
|
Motor power(KW) |
2.7 |
2.7 |
2.7 |
3.5 |
3.5 |
|
Steam consumption(kg/h) |
25 |
60 |
90 |
120 |
250 |
|
System vacuum (MPa) |
-0.085 |
-0.085 |
-0.085 |
-0.085 |
-0.085 |
|
Pressure of jacket(MPa) |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
|
Compressed air (MPa) |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
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Evaporation temperature(°C) |
60~100 |
60~100 |
60~100 |
60~100 |
60~100 |
Putting the raw materials into the main extraction tank is the first step in the extraction process. Solvents, like water, ethanol, or mixes of the two, are added based on the chemicals you want to work with.
Cell Wall Disruption Phase
At 20–40 kHz, ultrasonic tools make cavitation bubbles. When these very small bubbles pop, they break through cell walls and release sugars inside the cells into the solvent. It's possible for this mechanical action to happen without making too much heat.
Temperature-Controlled Extraction
A heat fluid that flows through the jacketed tank keeps the temperature exactly where it should be. For substances that can't handle high temperatures, like beta-glucans, you work at 40–60°C with a partial vacuum. In addition to keeping molecules from breaking down, this lowers the boiling point of the solvent.
Solid-Liquid Separation
When the extraction is done, the blend is sent to filter units that are built in. Filters with multiple stages get rid of plant matter and proteins, leaving behind clear extract liquor. When solutions are thick, high-torque agitators make sure they run easily without pump cavitation.
Concentration & Purification
The solution that has been filtered goes into vacuum evaporators, which are cold places where the liquid disappears. The highly concentrated extract has more carbohydrates, and the recovered solvents go back to the storage tanks through the purification tower, which achieves a recovery efficiency of 90–95%.
Alcohol Precipitation (Optional)
Chilled ethanol separates the basic carbohydrates to make them even purer. Low temperatures of -18°C are reached by the cooling jacket, which separates polysaccharides from small molecular pollutants.
Stage 1: Material Preparation
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Raw materials undergo cleaning and size reduction before loading into the extraction tank through top-mounted ports.
Stage 2: Solvent Addition & Heating
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PLC system automatically doses solvents according to preset solid-liquid ratios. Heating begins with continuous temperature monitoring.
Stage 3: UAE Activation
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Ultrasonic generators activate once target temperature is reached. Extraction proceeds for 24–40 minutes with programmable pulsing patterns.
Stage 4: Filtration
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Extract transfers via lobe pumps through inline filters. Residues discharge automatically through bottom valves.
Stage 5: Concentration
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Vacuum evaporator removes excess solvent while condenser captures vapors for recovery.
Stage 6: Final Processing
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Concentrated extract undergoes alcohol precipitation (if required), secondary filtration, and collection in sterile containers.
Stage 7: CIP Cleaning
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360° spray balls execute automated acid/alkali washing cycles without equipment disassembly.
Pharmaceutical Bio-Fermentation
Compounds that help the immune system can be taken out of Reishi, Cordyceps, and Turkey Tail mushrooms. For processing medicinal fungi, the tools can handle long extraction processes with high solid-to-liquid ratios.
Functional Food Manufacturing
Astragalus, Goji berries, and aloe vera are all plant-based ingredients that need to be handled carefully. Our method keeps the purity of bioactive compounds and handles the high-viscosity hydrocolloids that are common in mucilage extraction.
Marine Nutraceuticals
Specialized anti-corrosive setups can handle salty surroundings if you process seaweed for Fucoidan or Alginates. The polysaccharides extraction machine cleans extracts so they can be used in food supplement recipes.
Traditional Chinese Medicine
Dual-ultrasonic setups help the active ingredients dissolve faster, which is good for you. The system can handle lab research and development all the way up to full-scale factory production.
Cosmetic Ingredient Production
Pure, stable polysaccharides are needed in your beauty products. Controlled extraction temperatures protect the chemical structures that keep skin hydrated and fight age.
Beverage Industry
Plants can be used to get natural thickeners and supports. The clean design follows strict rules for preparing food and has cleaning methods that have been tested and proven to work.
Xi'an Bioland Instrument keeps strict quality standards that are backed up by foreign certifications:
Regular audits by outside parties are done at our production site. Each product comes with all the paperwork you need, like material certificates, pressure vessel records (if needed), and methods for making sure the machine works right.
Q: How does your system prevent thermal degradation of active compounds?
A: We utilize vacuum low-temperature concentration technology. Under vacuum conditions, water boils at approximately 45–50°C rather than 100°C. This preserves heat-sensitive polysaccharides while maintaining extraction efficiency.
Q: Can the machine handle both water extraction and ethanol precipitation?
A: Absolutely. Our multi-functional design includes jacketed tanks supporting hot water reflux extraction. The same vessel features cooling jackets for subsequent ethanol precipitation—no transfer between separate units needed.
Q: What solvent recovery rate should I expect?
A: High-efficiency configurations with integrated rectification towers achieve 90–95% ethanol recovery. This dramatically reduces your operating costs, especially important for large-scale commercial production.
Q: How do you manage high-viscosity residues?
A: We equip systems with high-torque scraping agitators and wide-channel lobe pumps. These components specifically handle viscous slurries without cavitation or motor overload—common problems with standard centrifugal pumps.
Q: What cleaning protocols are supported?
A: Every unit includes 360° rotary spray balls connected to CIP stations. Automated acid/alkali washing cycles reach all internal surfaces without disassembly. This ensures validation compliance for pharmaceutical manufacturers.
Q: Do you provide installation and training?
A: Yes. Our turnkey service includes workshop layout planning, equipment installation, operational commissioning, and comprehensive technical training for your team. We ensure smooth technology transfer.
Q: What's the typical lead time for customized systems?
A: Customized configurations require approximately 30 business days from order confirmation. Standard models ship within 5–7 business days. We provide weekly progress updates throughout manufacturing.
Q: Which materials contact the product?
A: All product-contact surfaces use SUS316L stainless steel with Ra ≤ 0.4µm surface finish. This prevents bacterial adhesion and resists corrosion from acidic or alkaline extraction solvents.
Ready to elevate your extraction capabilities with a polysaccharides extraction machine? Reach our technical team at info@biolandequip.com for customized solutions, quotations, or technical consultations. Let's discuss your specific requirements.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
