100 Liter Glass Reactor – Professional Pilot-Scale Chemical Processing Solution
The 100 liter glass reactor from Xi'an Bioland Instrument is a reliable pilot-scale processing vessel for scientific research and industrial manufacturing. Our reactor resists acids, alkalis, and organic solvents thanks to excellent GG17 borosilicate glass. Our precision control and wide temperature range of −80°C to 200°C ensure excellent conditions for complicated processes. Our double-sealing mechanism and spark-free motor ensure operating safety, while the transparent design enables you see phase shifts and colour transitions in real time. With over 15 years of manufacturing experience and CE/ISO certifications, we provide GMP/FDA-compliant equipment for pharmaceutical synthesis, botanical extraction, and polymer research.

Working Principle
A sophisticated thermodynamic control system powers your 100 litre glass reactor. The exterior jacket circulates heating or cooling fluids while the core vessel retains your reaction media. This design reduces essential exothermic reaction thermal lag.
The variable-frequency motor powers your anchor, paddle, or turbine stirring arrangement, guaranteeing homogenous mixing with high-viscosity materials. Down to 0.098 MPa, PTFE seals ensure vacuum integrity for low-temperature distillation and solvent recovery.
Temperature sensors supply the control system real-time data. Program accurate temperature ramps to prevent glass stress fractures and preserve reaction kinetics. Visual input from the transparent structure lets you alter settings based on process observation rather than blind monitoring.
The decreasing pressure of vacuum decreases boiling points. This shields temperature-sensitive chemicals during distillation. The flush bottom valve enables product residue-free discharge, essential for batch-to-batch uniformity.

Product features
-
The parts in contact with the materials are all made of high borosilicate glass (with a coefficient of expansion of 3.3) and polytetrafluoroethylene materials, which have stable performance and are not easy to react with the materials, making them convenient and safe to use.

- Unique frequency conversion speed regulation allows you to operate at high and low speeds in practice, with ideal accuracy and ease. It can be equipped with a fully explosion-proof system, dual display explosion-proof box digital display of speed and material temperature inside the kettle, stable performance, clear display of control and data plane, simple and easy to operate.

- The mixing system adopts ceramic bearings and mechanical seals to prevent wear and debris from the mixing rod. It is resistant to high temperature, wear-resistant, and has a good sealing effect.

- Adopting PT100 temperature sensor and glass thermometer sleeve.
- The vacuum pressure gauge displays real-time vacuum and the pointer displays.
- Crescent type stirring blade, 304 stainless steel+PTFE stirring blade; The material of the mixing rod is 304 stainless steel. Outsourced PTFE pipes have high strength and strong corrosion resistance.
- Glass+PTFE discharge valve, no liquid accumulation side discharge, very fast solution recovery.

Why Choose Us?
You get more than equipment when you work with Xi'an Bioland Instrument—you get a proven solution provider with knowledge.
Our products are CE, ISO, UL, ATEX, and IEC certified. Every unit meets GMP design requirements, ensuring quality and regulatory compliance.

Our in-house R&D team has years of engineering expertise. We design reactors to meet your process needs, not just sell them.
Visual Process Control: The transparent vessel solves a major industry issue. You may see reaction kinetics, foaming, and crystallization without disrupting your process, unlike steel reactors.
Superior Material Selection: We utilize genuine GG17 borosilicate glass with a thermal expansion value of 3.3 x 10^-6/K. Pharmaceutical API purity is maintained by preventing metallic contamination.
Anchor stirring for high-viscosity polymers or explosion-proof settings for volatile solvents—we customize the 100 liter glass reactor to your operation. Our custom lead time is 30 business days.
Comprehensive Support: Your project specialist sends weekly images and videos of production. Our facility provides Factory Acceptance Testing, one-year warranty, and lifelong maintenance.
Fast Shipping: Standard setups ship 5–7 days. For your deadline, we provide sea, rail, and air freight.
Technical Parameters
|
type
|
volume
(L)
|
Motor power
(W)
|
Speed
(r/min)
|
Stirring torque(1300r/min)
|
Inside/outside tube diameter
(mm)
|
Reactor vessel cover relevant opening size
|
|
|
|
|
|
|
|
center
|
left
|
right
|
later
|
before
|
|
BL-150
|
150
|
370
|
10-680
|
28000g.cm
|
600*550
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-100
|
100
|
250
|
|
22000g.cm
|
460*500
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-80
|
80
|
250
|
|
22000g.cm
|
460*500
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-50
|
50
|
180
|
|
15000g.cm
|
360*405
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-30
|
30
|
180
|
|
15000g.cm
|
315*360
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-20
|
20
|
120
|
|
12000g.cm
|
315*360
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-10
|
10
|
120
|
|
12000.g.cm
|
245*260
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-5
|
5
|
90
|
|
9000.g.cm
|
200*230
|
50#
|
29#
|
24#
|
24#
|
19#
|

Application Fields
Pharmaceutical & Biopharmaceutical: This reactor is used for multi-step API synthesis, deep-cooled peptide reactions, and particle-size-controlled crystallization. Your goods fulfill FDA clinical trial purity criteria because the inert glass surface inhibits heavy metal leaching.
Cannabis and hemp producers use our reactors to winterize ethanol. Using vacuum to recover ethanol at low temperatures preserves terpenes and cannabinoids. Your operators are protected from dangerous vapours by the explosion-proof motor.
Polymer & New Materials: High-torque stirring handles non-Newtonian fluids well for polymerization. Visualizing viscosity variations and gelling points helps you make uniform polymer batches and disperse graphene.
Fine Chemical Synthesis: Glass construction avoids metallic contamination in operations with strong acids, organic solvents, or corrosive intermediates.
Laboratory teams scaling up from benchtop use our 100L capacity to verify procedures before full production. infrastructure.
Quality Certification
We follow ISO 9001 throughout manufacture. Our electrical components are CE-certified for Europe. We provide ATEX-certified (ExdIIBT4) explosion-proof setups for Zone 1 hazardous settings.
GMP design, construction, and performance verification apply to all materials. Prior to shipment, our quality control team performs pressure, vacuum leak, and temperature cycling tests. Material certifications and test reports are included.
FAQ
Q: What thermal shock can the reactor handle?
A: We recommend limiting temperature changes to 70-80K. Ramped heating and cooling protocols protect glass integrity. Avoid introducing -20°C fluid into a 100°C jacket suddenly.
Q: Can this reactor handle positive pressure reactions?
A: Standard units are designed for vacuum and atmospheric pressure only. For processes exceeding 0.05 MPa positive pressure, consult us about specialized pressure-rated configurations.
Q: How do I maintain vacuum seal performance?
A: The PTFE rotary seal is a wear component. Inspect weekly in corrosive environments. Never run the agitator dry at high speeds, as friction heat damages seal faces. Use compatible lubrication when appropriate.
Q: Is Clean-In-Place (CIP) compatible?
A: Yes. Install spray ball attachments through top ports. Control spray pressure carefully to prevent glass damage, and ensure cleaning solvents are compatible with PTFE seals.
Q: What circulator specifications do I need?
A: We recommend minimum 3kW heating capacity and 1000W cooling at -20°C. Undersized circulators result in poor temperature control due to the thermal mass of 100 liters.
Q: How does glass compare to stainless steel for my application?
A: Glass provides superior corrosion resistance and visual monitoring. Choose glass when handling strong acids, when product purity is paramount, or when you need to observe reaction progress directly.
Contact Us
Ready to enhance your pilot-scale production with a 100 liter glass reactor? Contact our team at info@biolandequip.com for customized solutions, technical specifications, or to schedule a Factory Acceptance Test.