Pilot Plant Glass Reactor - Professional Scale-Up Solution for Chemical Process Development
Between lab R&D and full-scale manufacturing, Xi'an Bioland Instrument's pilot plant glass reactor is reliable. Our method helps you overcome the "scale-up effect" that causes yield losses during production growth with capacities from 10L to 200L. Reactors made of GG17 borosilicate glass, with thermal shock resistance (ΔT up to 110°C), provide real-time optical transparency for crystallization, phase separation, and reaction dynamics. Our modular platform unifies reaction, distillation, extraction, and condensation across a temperature range of -80°C to 250°C with vacuum capabilities of 0.098 MPa. We provide GMP-compliant pharmaceutical, chemical, and biotech equipment with CE, ISO, UL, and SGS certifications.

Features
1.The glass components are made of G3.3 borosilicate glass with good chemical and physical properties, such as: corrosion resistance and heat resistance.
2.Routinely applicable temperature range: high temperature experiment (maximum temperature is 200℃), low temperature experiment (minimum temperature is -80℃).
3.Frequency conversion speed control, gear motor, constant adjustable speed, low noise, strong torque, safe and stable.

4.PTFE paddles for stirring and mixing of low to high viscosity liquids(stirring paddle type selectable).
5.PTFE stirring paddle, suitable for stirring and mixing of low to high viscosity liquids. At the same time, you can choose different types of stirring paddles (anchor, paddle, frame and other mixing blades).
6.Other functional devices (explosion-proof device, PH monitoring, ultrasonic device, etc.) can be extended and customized according to specific needs.

Why Choose Xi'an Bioland Instrument?
Over 15 Years of Engineering Excellence
Process equipment for distillation, extraction, reaction, and separation is our specialty. Every unique project benefits from our in-house R&D team's decades of expertise.
Certified Quality You Can Trust
All reactors are CE, ISO, UL, and SGS-certified. Using GMP/FDA standards, we ensure your process satisfies regulatory criteria from the start.
True Customization, Not Just Configuration
A specific stirring speed? Unusual temperature range? Ultrasonic extraction or integrated filtration? We customize reactor volume, jacket design, stirring type (anchor, paddle, turbine), and automation level (manual to full PLC control) to your operation.

Full Production Transparency
A project manager posts photographs and videos weekly to follow your purchase. You obtain specific inspection media or book a Factory Acceptance Test (FAT) at our location before shipping.
Fast Turnaround
Standard models ship 5–7 days. Custom configurations are ready in 30 business days with sea, rail, or air freight options.
Comprehensive Support
Lifetime maintenance and one-year warranty. Our technical team helps with installation, troubleshooting, and process optimization.
Proven Track Record
We've supplied Europe and Southeast Asia's pharmaceutical, biopharmaceutical, and chemical intermediate businesses with turnkey solutions.
Technical Parameters
|
type
|
volume
(L)
|
Motor power
(W)
|
Speed
(r/min)
|
Stirring torque(1300r/min)
|
Inside/outside tube diameter
(mm)
|
Reactor vessel cover relevant opening size
|
|
|
|
|
|
|
|
center
|
left
|
right
|
later
|
before
|
|
BL-150
|
150
|
370
|
10-680
|
28000g.cm
|
600*550
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-100
|
100
|
250
|
|
22000g.cm
|
460*500
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-80
|
80
|
250
|
|
22000g.cm
|
460*500
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-50
|
50
|
180
|
|
15000g.cm
|
360*405
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-30
|
30
|
180
|
|
15000g.cm
|
315*360
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-20
|
20
|
120
|
|
12000g.cm
|
315*360
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-10
|
10
|
120
|
|
12000.g.cm
|
245*260
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-5
|
5
|
90
|
|
9000.g.cm
|
200*230
|
50#
|
29#
|
24#
|
24#
|
19#
|
Working Principle
In a tight, controlled environment, your pilot plant glass reactor performs chemical reactions, distillations, and extractions.
Heating/Cooling:
The double jacket transfers heat to and from the reaction mixture via thermal fluid. An external thermostat ensures ±1°C set-point precision.
Agitation:
The vessel's PTFE-coated impeller is driven by a high-torque motor. Stirring speeds mass transfer, maintains temperature, and reduces sedimentation and fouling.
Vacuum Operation:
Reduce internal pressure using a vacuum pump to reduce boiling points for gentle solvent evaporation or oxygen-free processes.
Reflux & Distillation:
Top-mounted glass condenser brings vapour up. Condensed liquid refluxes or distills in a receiver flask.
Material Addition:
Use dropping funnels or automated dosing pumps to add reagents via the top lid ports for exact stoichiometry.
Monitoring:
Real-time colour changes, phase separation, and crystal formation are possible with transparent walls, which optimizes processes.

Application Fields
- Biological and pharmaceutical: making APIs, linking peptides, making intermediates, and putting together drugs
- Polymer polymerization, custom chemical synthesis, and catalytic reactions are processes used in chemical manufacturing.
- Beverage and Food: Extracting flavours, distilling essential oils, and scaling up fermentation
- Ingredient synthesis, scent mixing, and emulsification are all processes used in cosmetics.
- Gasoline and petrochemicals: refining methods, developing additives, and testing fuel
- leaching, cleansing, and recovery methods for precious metals and metallurgy
- Making nanomaterials, coming up with coatings, and making battery electrolytes are all examples of new materials.
- Making active ingredients and testing formulations for pesticides and agrochemicals
Quality Certification
For European markets, Xi'an Bioland Instrument has both ISO 9001 quality control approval and CE conformity marking. We offer UL, SGS, ATEX, and IECEx certification for explosion-proof setups upon request. Each product goes through the following:
- Checks for leftover heat stress in glass that could lead to failure with the Polariscope Stress Inspection.
- Testing for Vacuum Leak Rate: Makes sure the seal is solid (less than 2 mbar/hour leak rate).
- Checks that the jacket joins at 1.5 times the working pressure through hydrostatic jacket testing.
- Measurement of Agitator Run-Out: Makes sure that the shaft wobble is less than 0.5 mm to avoid vibration cracks.
- Material Certification: All GG17 glass and PTFE parts can be tracked back to their original sources in line with GMP rules.

FAQ
Q1: What is the safe thermal shock limit for your reactors?
A: Our GG17 glass handles ΔT of 60°C–110°C depending on volume. We recommend programming gradual ramps on your thermostat to avoid stress fractures.
Q2: Can I run overpressure reactions?
A: Standard units are rated for vacuum and atmospheric pressure. For pressures above 0.5 bar, order our reinforced pressure-reaction glass models (up to 12 bar) with polycarbonate shields.
Q3: Which stirring impeller should I choose?
A: Use Anchor impellers with PTFE scrapers for high-viscosity materials (polymers, creams). Choose Propeller or Pitch-Blade impellers for suspensions and crystallization to prevent settling.
Q4: How do you ensure long-term sealing performance?
A: We use dry-running PTFE mechanical seals or magnetic couplings. For deep vacuum (< 10 mbar), ceramic-face seals are standard. Inspect seals periodically per your maintenance schedule.
Q5: Is the reactor compatible with Clean-In-Place systems?
A: Yes. Our lids accept low-pressure 360° spray balls designed for glass. This ensures complete solvent coverage without mechanical impact damage.
Q6: What delivery time can I expect?
A: Standard models ship in 5–7 days. Customized reactors require approximately 30 business days with full photo/video progress updates.
Q7: Do you offer installation and training?
A: Absolutely. We provide remote installation guidance, on-site commissioning (upon request), and operator training to ensure safe, efficient operation.
Contact Us
Ready to safely and effectively grow your process with a pilot plant glass reactor? Contact info@biolandequip.com for bespoke prices, technical datasheets, and project consultancy.