Chemical Glass Reactor – Precision Reaction Equipment for Laboratory & Production
Xi'an Bioland Instrument's chemical glass reactor, made of excellent GG17 borosilicate glass, performs reaction synthesis, distillation, extraction, and mixing under exact temperature and vacuum control. This transparent reactor operates from −80°C to 200°C, reducing contamination hazards and allowing real-time reaction dynamics monitoring. Our systems include spark-free motors, double sealing, and PLC automation. We provide GMP-compliant equipment trusted by pharmaceutical, chemical, and materials research industries globally with over 15 years of production experience and CE/ISO certifications.

Why Choose Xi'an Bioland's Glass Reaction Systems?
Unmatched Quality & Safety Standards
Our reactors are CE, ISO, UL, SGS, ATEX, and IEC certified. Each item satisfies GMP/FDA design, material, and performance standards. Secure operation is provided by spark-free motors, lift-and-rotate safety devices, and double mechanical sealing.
Superior Chemical Compatibility
GG17 borosilicate glass resists strong acids, alkalis, and organic solvents without leaching metals. For pharmaceutical APIs and high-purity chemical synthesis, trace contaminants reduce yields.

Complete Process Visibility
The transparent vessel eliminates steel reactor "black box" issues. Real-time phase separation, colour changes, foaming, and mixing patterns are possible. Visibility greatly enhances experimental repeatability and increases R&D speed.
Extreme Temperature Precision
Our jacketed design provides perfect heat regulation from -80°C to 200°C. Utilizing vacuum systems with <0.098 MPa enables effective low-temperature crystallization and high-temperature reflux in one unit.
Modular Flexibility & Automation
Conventional ground joints fit condensers, dropping funnels, temperature sensors, and rectification columns. With your processes, your product can change. PLC integration, explosion-proof designs, and fully automated lift-and-rotate systems for industrial processes are supported.
Comprehensive Customization
We tailor vessel volumes, stirring types (anchor, paddle, turbine), heating/cooling capacities, and structural configurations to your exact specifications. Whether you need a 5L benchtop unit or a 200L pilot reactor, we deliver within 30 business days for custom orders and 5–7 days for standard models.

Proven Engineering Support
Our in-house R&D team provides full-process solutions—from ultrasonic extraction and peptide synthesis to vacuum distillation and crystallization systems. Weekly production updates with photos/videos keep you informed. We offer Factory Acceptance Testing (FAT) before shipment and lifetime maintenance backed by a one-year warranty.

Technical Parameters
|
type
|
volume
(L)
|
Motor power
(W)
|
Speed
(r/min)
|
Stirring torque(1300r/min)
|
Inside/outside tube diameter
(mm)
|
Reactor vessel cover relevant opening size
|
|
|
|
|
|
|
|
center
|
left
|
right
|
later
|
before
|
|
BL-150
|
150
|
370
|
10-680
|
28000g.cm
|
600*550
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-100
|
100
|
250
|
|
22000g.cm
|
460*500
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-80
|
80
|
250
|
|
22000g.cm
|
460*500
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-50
|
50
|
180
|
|
15000g.cm
|
360*405
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-30
|
30
|
180
|
|
15000g.cm
|
315*360
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-20
|
20
|
120
|
|
12000g.cm
|
315*360
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-10
|
10
|
120
|
|
12000.g.cm
|
245*260
|
50#
|
40#
|
34#
|
34#
|
29#
|
|
BL-5
|
5
|
90
|
|
9000.g.cm
|
200*230
|
50#
|
29#
|
24#
|
24#
|
19#
|
Working Principle
The reactor uses mechanical agitation and jacketed thermal circulation. An external chiller or heater controls oil or ethanol heat transfer fluid in the double-wall jacket to maintain exact temperatures. Homogeneous mixing without sparks is achieved by rotating the stirring shaft in the tank with PTFE mechanical seals.
A vacuum pump reduces internal pressure to decrease boiling temperatures for gentle distillation or solvent recovery at the top port. Vapours are captured and returned via side port condensers. Clear borosilicate provides constant monitoring of reaction progress, bubble formation, and phase transitions without opening the system.
Ground-glass joints allow modular connection of dropping funnels for controlled reagent addition, thermowells for precision temperature detection, and reflux columns for fractional distillation while retaining vacuum integrity.

Process Flow
- Install the chemical glass reactor on a sturdy frame. Join jacket inlets to circulator. Ground joints connect condensers, vacuum pump, and probes.
- Load raw ingredients through the top flange or side addition funnel. Seal all ports and check vacuum.
- Temperature Control: Start jacket circulation. Gradually increase temperature (≤5°C/min) to prevent thermal shock. Digital controller monitoring.
- Start the stirrer at appropriate rpm. The glass shows homogeneous mixing. If required, add reagents dropwise.
- Vacuum Work: Vacuum or inert environment aids low-boiling solvent evaporation. Adapt pressure to process demands.
- Vapours ascend into the condenser, liquefy, and collect in receiving flasks. Visually check distillate clarity.
- Discharge and cool the reactor slowly. Gently release vacuum. Use bottom valve or top opening to discharge product.
- Cleaning: Use CIP-compatible solvents. Use ultrasonic cleaning instead of mechanical scraping.

Application Fields
Pharmaceutical & Biopharmaceutical
Synthesise APIs, peptides, and intermediates under GMP. Drug purity is protected from metal-ion contamination by the inert glass surface. Low-temperature coupling processes are possible using cryogenics.
Chemical Research & Development
Screen catalysts, polymerize, and study reaction kinetics. Visual monitoring boosts optimization. Modular attachments change with experiments.
Petrochemical Processing
Test hydrogenation, cracking, and solvent recovery on pilot scale. Chemical resistance handles harsh hydrocarbons and halogens without degradation.
New Materials & Electronics
Make pure lithium battery electrolytes, graphene precursors, and semiconductor compounds. Ultra-low impurities are achieved via vacuum distillation at regulated temperatures.
Food & Cosmetics
Synthesize emulsifiers, concentrate flavours, and extract essences. The clear vessel ensures phase separation and homogeneity, satisfying food-safety regulations.
Metallurgy & Precious Metals
Refine and purify noble metals through acid digestion and controlled precipitation. Glass compatibility with strong acids avoids cross-contamination.
Quality Certification
Xi'an Bioland Instrument holds:
- CE Certification: European safety and health standards compliance
- ISO Certification: Quality management system verification
- GMP Compliance: Design, materials, and performance meet pharmaceutical manufacturing standards
- Additional Approvals: UL, SGS, ATEX, IEC certifications ensure global operational safety
All materials and welding processes undergo rigorous inspection. We provide material traceability reports and pressure test certificates with each unit.

FAQ
Q1: What temperature ramp rate is safe?
Keep changes ≤5°C/min to prevent thermal shock. Borosilicate glass tolerates ΔT ≈100–120K, but gradual transitions extend vessel lifespan.
Q2: Can I use steam for heating?
No. Glass jackets are designed for circulating fluids at ≤0.5 bar. High-pressure steam risks rupture. Use hot oil circulators instead.
Q3: Is the reactor compatible with hydrofluoric acid?
No. HF etches glass immediately. Strong hot alkalis (>100°C NaOH) also degrade the silicone structure over time.
Q4: How do I fix vacuum leaks?
Check PTFE O-rings at the stirrer shaft and replace if worn. Reapply high-vacuum grease to all ground joints and tighten clamps evenly.
Q5: What's the lead time for custom orders?
Custom reactors ship in 30 business days. Standard models are ready in 5–7 days. We provide weekly progress updates with photos.
Q6: Do you offer installation and training?
Yes. We supply detailed manuals, video guides, and remote support. On-site training and FAT are available upon request.
Contact Us
Ready to enhance your reaction processes with a chemical glass reactor? Reach out for custom solutions and technical consultation: info@biolandequip.com