Xi'an Bioland Instrument Co., Ltd. specializes in chemical engineering reactors for pharmaceutical, chemical, and food processing applications. Our reactors operate from −80°C to 200°C, built with GG17 borosilicate glass and spark-free motors. PLC-automated control, double mechanical sealing, and multi-function capability — reaction, distillation, extraction, and vacuum — deliver reliable performance for R&D labs and industrial production alike. CE and ISO certified, GMP compliant, OEM/ODM available.
1. Precise Jacket Temperature Control
Heating or cooling media circulates through the sealed jacket, maintaining temperatures from −80°C to 200°C with ±0.5°C accuracy. For exothermic pharmaceutical synthesis, this prevents thermal deviation that leads to batch rejection or safety incidents.
2. Spark-Free Motor with Double Mechanical Seal
The explosion-proof motor and dual-seal shaft design eliminate ignition risk when processing flammable solvents — a mandatory requirement for solvent extraction and API synthesis environments.
3. Full-View GG17 Glass Vessel
Borosilicate glass provides direct visual access to your reaction. Track color shifts, phase separation, and mixing behavior in real time without breaking process continuity.
4. Modular Peripheral Connections
Standard ports accommodate condensers, pressure-equalizing funnels, temperature probes, and sampling valves. Reconfigure for different protocols without modifying the base unit.
5. PLC Automation with Real-Time Monitoring
The integrated PLC panel controls stirring speed, temperature, and vacuum level simultaneously. Alarm thresholds can be set for each parameter to flag deviations before they affect product quality.
Step 1 — Load & Seal
Reactants are charged into the glass vessel through the top port. All fittings are sealed via PTFE gaskets and double mechanical seals on the agitator shaft.
Step 2 — Set Thermal Conditions
The jacket inlet connects to your circulating bath or chiller. The PLC monitors vessel temperature and adjusts flow rate to maintain your target setpoint.
Step 3 — Run the Process
Stirring speed, vacuum level, and temperature are controlled simultaneously through the PLC panel. For distillation, the connected condenser and collection flask capture solvent within the closed system.
Step 4 — Monitor & Adjust
The transparent vessel allows real-time visual inspection. Process data is displayed on the control panel and can be logged for batch records.
Step 5 — Clean & Inspect
316L stainless steel contact parts and PTFE seals support CIP cleaning. Ra < 0.4μm surface finish on metal parts prevents residue buildup between batches.
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Component
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Material
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Purpose
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Vessel Body
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GG17 Borosilicate Glass
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Chemical inertness, thermal resistance, visual access
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Metal Contact Parts
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316L Stainless Steel
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Corrosion resistance, GMP compliance
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Seals & Gaskets
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PTFE
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Solvent resistance, contamination prevention
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Agitator Options
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Paddle / Anchor / Helical Ribbon
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Matched to fluid viscosity and heat transfer needs
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Agitator Selection Guide:
· Low-viscosity fluids → Paddle agitator (standard)
· Medium-to-high viscosity → Anchor agitator (improved wall contact)
· High-viscosity or heat-sensitive materials → Helical ribbon (maximum wall-scraped heat transfer)
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Industry
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Typical Use Case
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Why This Reactor Fits
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Pharmaceutical API Synthesis
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Multi-step batch reactions
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Precise temperature staging, GMP-compliant surfaces
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Natural Product Extraction
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Solvent-based plant extraction
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Vacuum capability, closed system, spark-free motor
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Polymer Research
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Controlled polymerization
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Defined temperature and mixing profiles
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Food & Beverage
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Flavor compound reactions
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GMP/CE certified, food-contact material standards
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Specialty Chemicals
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Small-batch synthesis
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Flexible configurations, visual monitoring
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Cosmetic Manufacturing
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Emulsification and active compound processing
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CIP-compatible, contamination-free sealing
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Bioland chemical engineering reactors are certified to CE and ISO standards. All units are designed and produced in compliance with GMP requirements, making them suitable for pharmaceutical and food-grade applications.
Pre-Shipment Quality Checks:
· Hydrostatic pressure qualification test
· Weld integrity verification
· Surface roughness confirmation (Ra < 0.4μm on sanitary-grade contact parts)
· Dimensional inspection against drawing
Factory Acceptance Test (FAT):
Customers may schedule an on-site FAT at our Xi'an facility. Full documentation — including inspection records, test data, and video footage — is provided before shipment release.
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type
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volume
(L)
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Motor power
(W)
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Speed
(r/min)
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Stirring torque(1300r/min)
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Inside/outside tube diameter
(mm)
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Reactor vessel cover relevant opening size
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||||
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center
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left
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right
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later
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before
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BL-150
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150
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370
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10-680
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28000g.cm
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600*550
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50#
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40#
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34#
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34#
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29#
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BL-100
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100
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250
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22000g.cm
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460*500
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50#
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40#
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34#
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34#
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29#
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BL-80
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80
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250
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22000g.cm
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460*500
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50#
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40#
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34#
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34#
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29#
|
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BL-50
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50
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180
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15000g.cm
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360*405
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50#
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40#
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34#
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34#
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29#
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BL-30
|
30
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180
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15000g.cm
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315*360
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50#
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40#
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34#
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34#
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29#
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BL-20
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20
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120
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12000g.cm
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315*360
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50#
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40#
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34#
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34#
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29#
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BL-10
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10
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120
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12000.g.cm
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245*260
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50#
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40#
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34#
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34#
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29#
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BL-5
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5
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90
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9000.g.cm
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200*230
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50#
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29#
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24#
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24#
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19#
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· 15 years of reactor manufacturing experience across pharmaceutical, chemical, and food industries
· In-house R&D team handles custom engineering — no third-party intermediary delays
· OEM/ODM projects accepted with full documentation support
· 5–7 business days standard lead time; 30 business days for custom configurations
· Weekly production updates with photo or video records — you track progress without chasing
· Global shipping via sea, rail, and air freight with freight documentation support
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Support Type
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Coverage
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Warranty
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1 year — parts and workmanship
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Technical Support
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Lifetime — remote diagnosis and guidance
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Spare Parts
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Long-term supply guaranteed
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On-Site Service
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Available by arrangement
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Documentation
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CE/ISO certificates, test reports, manuals included
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Tell us your vessel volume, temperature requirements, and target application — we'll respond within 24 hours with a configuration recommendation and pricing.
What to include in your inquiry:
· Required vessel volume (liters)
· Temperature range and control medium
· Process type (reaction / distillation / extraction / vacuum)
· GMP or pressure certification requirements
· Approximate timeline
Q: Can the glass vessel handle full vacuum conditions?
A: Yes. GG17 borosilicate glass and sealed fittings support vacuum operation down to the levels required for low-pressure distillation and solvent recovery.
Q: What agitator should I choose for high-viscosity materials?
A: For viscous fluids, anchor or helical ribbon agitators scrape the vessel wall, improving heat transfer uniformity and preventing localized hot spots that damage heat-sensitive products.
Q: What safety systems prevent thermal runaway?
A: The reactor uses spark-free motors, double mechanical seals, and PLC-controlled alarm thresholds. It can also be integrated with external temperature interlock systems and pressure relief valves.
Q: How do I specify a custom reactor configuration?
A: Share your vessel volume, temperature range, agitator type, port layout, and any GMP or pressure rating requirements. Our engineering team will produce a configuration drawing for your review before production begins.
Q: What cleaning process is compatible with this reactor?
A: CIP (Clean-in-Place) is supported. PTFE seals and 316L stainless steel contact parts are compatible with standard pharmaceutical cleaning agents. Ra < 0.4μm surface finish minimizes residue adhesion.
Q: Is GMP documentation available for regulatory submissions?
A: Yes. We provide CE and ISO certificates, material certificates for wetted parts, surface roughness reports, and FAT records to support your regulatory documentation requirements.
If you want to get information about the chemical engineering reactor, please contact us at info@biolandequip.com.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
