The enterprise-grade low temperature vacuum concentrator from Xi'an Bioland Instrument Co., Ltd. is designed to remove solvents precisely without heating up. Our system is 50–500% more efficient at extracting than traditional ways when it works at 20–40°C under controlled vacuum (10–100 mbar). The equipment can handle samples in just 24 to 40 minutes, cutting cycle time by more than two thirds. It has PLC computer control and is completely explosion-proof. Our product is made of high-quality 316 stainless steel, has built-in solvent recovery that works more than 95% of the time, and is fully compliant with GMP and FDA regulations. We offer unique solutions and committed engineering help throughout your production journey. Our work is backed by CE and ISO certifications.
Proven Engineering Excellence
Because they have been making chemical process tools for over 15 years, our in-house R&D team brings a lot of knowledge to every job. We don't just sell tools; we also provide complete options that are made to fit your needs.
Unmatched Quality Standards
When we make things, we follow strict international rules. To make sure they work well in harsh settings for a long time, all of the units go through strict vacuum leak integrity testing and material verification (PMI).
Intelligent Automation
Fully automatic PLC control systems make things easier to use. You'll need to do less work by hand, but the effects will be the same across batches. Monitoring in real time keeps you up to date at all times.
Comprehensive Support
Our skilled expert team is here for you, from planning the workshop to doing care after the sale. During production, we send weekly updates with photos and movies of the progress. You get full paperwork before the shipment, or you can make an appointment for a Factory Acceptance Test at our site.
Flexible Manufacturing Options
Need changes made? We're great at OEM and ODM services. Standard types can be sent out in 5–7 days, while custom equipment takes 30 business days to ship. Pick either sea, train, or air freight based on when you need it.
Lifetime Partnership
Our guarantee lasts for one year and includes free upkeep for life. We are dedicated to your success and will always be here to help you with technology issues and respond quickly when you need it.
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Technology parameter |
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|
Model |
BL-TN-C50L |
BL-TN -C100L |
BL-TN -C200L |
BL-TN -C300L |
BL-TN -C500L |
|
Volume (L) |
50 |
100 |
200 |
300 |
500 |
|
Evaporation capacity (kg/h) |
20 |
50 |
70 |
100 |
200 |
|
Motor power(KW) |
2.7 |
2.7 |
2.7 |
3.5 |
3.5 |
|
Steam consumption(kg/h) |
25 |
60 |
90 |
120 |
250 |
|
System vacuum (MPa) |
-0.085 |
-0.085 |
-0.085 |
-0.085 |
-0.085 |
|
Pressure of jacket(MPa) |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
|
Compressed air (MPa) |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
|
Evaporation temperature(°C) |
60~100 |
60~100 |
60~100 |
60~100 |
60~100 |
Advanced thermal concepts are used by our condenser to make evaporation gentle and effective. Simply follow these steps:
Vacuum Creation
The room pressure drops by a huge amount when a high-performance vacuum pump is used. This makes your liquids' boiling point lower, which lets them evaporate at temperatures well below those found in the air.
Controlled Heating
The warmth stays just right with PID-controlled heating coats or built-in heat pump systems. Your set limits are never exceeded by the system, which keeps sensitive chemicals safe from thermal stress.
Efficient Mass Transfer
Customized jar shape makes the most of the surface area of the liquid. The vacuum climate speeds up the evaporation of molecules and stops oxidation and other unwanted chemical processes.
Condensation & Recovery
The liquids that have evaporated are sent to a special cooling device. They turn back into liquids here and are ready to be used again. With this closed-loop method, more than 95% of the useful liquids are captured, which cuts down on trash and costs.
Anti-Foaming Technology
Modern devices that stop bumping keep liquid surfaces solid. The chance of cross-contamination goes down a lot whether you're working with toxic organics or biological data.
Step 1: Sample Loading
Put your mix into the jar for evaporation. The system can handle different amounts, from millilitres in a lab to large batches in a commercial setting.
Step 2: Parameter Setting
The PLC's easy-to-use screen lets you enter the goal temperature and vacuum level. The system saves your codes so that they can be used again and again.
Step 3: Set up the vacuum
The pump takes the air out of the cylinder. Monitoring the pressure in real time makes sure that everything is perfect before the heating starts.
Step 4: Evaporation under control
Solvent evaporation starts with gentle heating. As the process goes on, sensors keep changing settings to keep things stable.
Step 5: Get the solvent back.
In the cooling system, vapours cool down. The recovered solvent is put in a different jar until it can be checked for quality and used again.
Step 6: Finishing the concentration
The system will let you know when the desired concentration level is reached. While the machine gets ready for the next batch, let your concentrated product go.
Step 7: Clean the CIP (optional).
Turn on the automatic Clean-in-Place cycle for GMP uses. Spray balls and self-draining shapes make sure that all waste is removed completely between runs.
Biopharmaceutical Manufacturing
Upstream processing fluids that contain DNA/RNA, monoclonal antibodies, and other proteins should be concentrated using a low temperature vacuum concentrator. Keep the bioactivity while the buffer and liquid are being taken out of the filtration steps.
Natural Product Extraction
Use plant products to make nutraceuticals and makeup. Our tools can handle stevia, propolis, curcumin, and mushroom products without changing the active ingredients.
Food & Beverage Industry
Make fruit drinks, flavourings, and scented oils more concentrated. Vacuum action keeps terpenes and esters from oxidizing, which keeps the original flavours without turning brown.
Chemical Synthesis
Take away chemical solvents from reaction mixes, such as DMSO, DMF, and dichloromethane. Get back useful chemicals while keeping temperature-sensitive intermediates safe.
Environmental Compliance
Zero Liquid Discharge (ZLD) uses are used to clean up industry wastewater. Metalworking fluids and polishing solutions can be concentrated to cut the amount of sludge by up to 90%.
Pharmaceutical R&D
Lab-scale units help with the development and creation of APIs. During the drug finding process, rapid processing lets iterations happen more quickly.
Specialty Chemicals
Handle unique chemicals that are very valuable and need to be processed carefully. Custom materials, like Titanium and Hastelloy, can stand up to harsh chemical conditions.
Xi'an Bioland Instrument has strict quality standards for all of its production processes:
We keep track of all test results and give you full qualification packages to back up your validation methods.
FAQ
Q: How does the system handle foaming samples during concentration?
A: Our equipment incorporates specialized bumping prevention technology. The design controls surface tension to minimize foam formation and prevent sample loss or cross-contamination during processing.
Q: Can you concentrate high-boiling point solvents effectively?
A: Absolutely. While solvents like DMSO boil at high temperatures atmospherically, our vacuum system reduces pressure below 10 mbar. This depresses DMSO's boiling point to approximately 40-50°C, enabling safe evaporation without thermal damage.
Q: What maintenance does the vacuum pump require?
A: For oil-free diaphragm pumps, we recommend inspection every 3,000 operating hours. Rotary vane pumps need oil changes every 500-1,000 hours depending on solvent exposure. We specify acid-resistant pumps for corrosive applications to extend service life.
Q: How does your system compare to standard rotary evaporators?
A: Our heat pump models capture condensation's latent heat and recycle it to the evaporation side. This achieves a Coefficient of Performance (COP) exceeding 4, delivering significantly higher energy efficiency than rotary evaporators relying solely on external heating baths.
Q: Is the equipment compatible with automated cleaning protocols?
A: Yes. Industrial models feature spray ball systems and self-draining geometry designed for Clean-in-Place (CIP) cycles. This ensures complete residue removal between batches in GMP-compliant environments.
Q: What lead times can I expect for orders?
A: Standard configurations ship within 5-7 business days. Customized solutions typically require 30 business days. We provide weekly progress updates throughout production.
Q: Do you offer installation and training support?
A: Certainly. Our turnkey service includes on-site installation, commissioning, and comprehensive operator training. Technical support continues throughout your equipment's operational life.
Ready to enhance your concentration processes with a low temperature vacuum concentrator? Reach out to our technical team at info@biolandequip.com for customized solutions and expert guidance.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
