The enterprise-grade reflux extraction apparatus offered by XI'AN BIOLAND INSTRUMENT CO., LTD. is designed for maximum extraction effectiveness and dependability. With more than 15 years of experience in production, our systems get 50–500% higher yields than old-fashioned ways. The quality 316 stainless steel used in the building of each unit is CE and ISO certified. Each unit supports multiple extraction processes, such as hot reflux and solvent recovery, and comes with the option of PLC automation for easy integration into your production line. Our methods for extracting compounds work at controlled temperatures between 40°C and 60°C to protect compounds that are sensitive to heat. They can finish extraction processes in just 24 to 40 minutes and fully meet GMP/FDA standards for pharmaceutical and food-grade uses.
The gear you use for your business needs to be reliable. We are licensed by CE, ISO, UL, and SGS. From the time it is designed to the time it is used, every system meets GMP compliance standards. For controlled businesses, you get equipment that is ready to go with paperwork.
Results that are important to your bottom line are produced by our product. When compared to traditional ways, extraction times will be cut by more than 66%. The dual-condenser setup improves liquid collection rates the most. Your yields of active ingredients go up by a huge amount while the purity of the substance is maintained.
Modern output needs modern ways to do things. Temperature, pressure, and time factors can be automatically set by our optional PLC control system. The explosion-proof design makes sure that flammable liquids can be used safely. You are sure of yourself when working in tough industry settings.
Not every facility is the same. We offer OEM/ODM options that are made to fit your process. You can pick from different tank sizes, condenser layouts, and material grades. The engineers on our team create complete systems that include cleaning with CIP, recovering solvents, and setting off automatic discharge modules.
Your work has to be done now. Within 30 business days, customized products are sent out. It takes 5–7 days for standard units to arrive. You get reports on your progress every week, along with photos and videos. Our expert team offers warranty covering for one year and lifelong maintenance support.
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Technology parameter |
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Model |
BL-TN-C50L |
BL-TN -C100L |
BL-TN -C200L |
BL-TN -C300L |
BL-TN -C500L |
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Volume (L) |
50 |
100 |
200 |
300 |
500 |
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Evaporation capacity (kg/h) |
20 |
50 |
70 |
100 |
200 |
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Motor power(KW) |
2.7 |
2.7 |
2.7 |
3.5 |
3.5 |
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Steam consumption(kg/h) |
25 |
60 |
90 |
120 |
250 |
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System vacuum (MPa) |
-0.085 |
-0.085 |
-0.085 |
-0.085 |
-0.085 |
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Pressure of jacket(MPa) |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
0.09~0.3 |
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Compressed air (MPa) |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
0.5~0.6 |
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Evaporation temperature(°C) |
60~100 |
60~100 |
60~100 |
60~100 |
60~100 |
For the best mass movement, the device uses constant thermodynamic cycling. The way your extraction process works is this:
Flow of the fluid: The heated jacket boils your fluid in a controlled way. As vapour rises through the material bed, it keeps pulling out target chemicals.
Return and condensation: Hot vapour comes into the high-efficiency condenser. Cooling water to 20°C below its boiling point makes sure that all of the water condenses. Concentration gradients are kept by adding new liquid to the extraction tube.
Better Extraction: Ultrasonic units that can be added cause cavitation effects. These tiny bubbles break down cell walls, which lets more active ingredients out. It stops channelling and makes sure that all surfaces make touch evenly.
Working with vacuum: For chemicals that are sensitive to heat, vacuum lowers the boiling point. At 40–60°C, you can remove delicate molecules while keeping their bioactivity and effectiveness.
Monitoring All the Time: Level signs, temperature sensors, and pressure gauges send information to the control system all the time. For reliable results, PLC automation changes settings in real time.
Step 1: Material Loading → Load pre-sized botanical material into the extraction tank through the top access port.
Step 2: Solvent Addition → Introduce your chosen solvent (ethanol, water, or organic solvent) to achieve proper solid-liquid ratio.
Step 3: Heat & Reflux → Activate heating system. Solvent begins circulating through condenser in continuous reflux.
Step 4: Extraction Cycle → Maintain optimal temperature for 24–40 minutes while monitoring concentration levels.
Step 5: Separation → Drain enriched extract through bottom valve with integrated filtration.
Step 6: Solvent Recovery → Optional recovery system distills used solvent for reuse, reducing operational costs.
Step 7: CIP Cleaning → Automated cleaning-in-place system prepares equipment for next batch without disassembly.
Extract alkaloids, flavonoids, and terpenes from botanical sources. Process materials like stevia, propolis, curcumin, and mushroom extracts. Maintain API purity for drug synthesis and pharmaceutical intermediates.
Isolate essential oils, natural colorants, and flavor compounds. Determine fat content following AOAC standards. Extract functional ingredients while meeting food-grade safety requirements.
Obtain plant-based active ingredients for skincare formulations. Extract antioxidants, vitamins, and aromatic compounds. Process heat-sensitive materials without degradation.
Perform EPA Method 3540C compliant extractions. Analyze soil and sludge for semi-volatile organic compounds. Extract pesticides and PCBs for regulatory testing with required recovery rates.
Support laboratory-scale process development. Test extraction parameters before industrial scaling. Validate new compound isolation methods with reproducible results.
Our manufacturing facility maintains comprehensive quality management systems. We hold ISO 9001 certification for quality management and CE marking for European market compliance. Every reflux extraction apparatus undergoes rigorous factory acceptance testing before shipment.
Our quality control process includes vacuum leak integrity testing (maintaining <10 Torr for 60+ minutes), hydrostatic pressure testing at 1.5x design pressure, and dimensional tolerance verification of all ground glass joints. You receive complete test documentation with each system.
All materials contacting your product meet FDA food-grade standards. Borosilicate glass components conform to ISO 3585 and ASTM E438 Type I specifications. Stainless steel construction uses certified 304 or optional 316L grades.
FAQ
Q1: How do I prevent solvent channeling during operation?
Ensure uniform particle size of your feed material. Maintain consistent packing density if using thimble-type configurations. For reactor vessels, use our overhead stirrer with pitched-blade impeller to keep material suspended.
Q2: Why might solvent recovery rates be lower than expected?
Check your condenser performance first. Verify cooling fluid temperature stays 20°C below solvent boiling point. Inspect all joints for proper sealing and examine PTFE components for wear.
Q3: Can your system handle high-viscosity solvents?
Yes, with appropriate modifications. We recommend mechanical agitation systems and wider bore return lines. Our engineers will configure your system for optimal flow characteristics.
Q4: What cleaning protocol prevents cross-contamination?
Follow triple rinse with extraction solvent, then clean glass components appropriately. Use ultrasonic cleaning for sintered filters. All components undergo oven drying before next use.
Q5: How do I prevent joint seizing during high-temperature operations?
We recommend PTFE joint sleeves for aggressive solvents. These provide chemical-resistant, non-stick sealing that prevents freezing even after prolonged heating cycles.
Ready to use a reflux extraction apparatus to improve your extraction? Our technological staff designs bespoke solutions. Reach us at info@biolandequip.com for detailed quotations and technical consultations.
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2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.