Xi'an Bioland Instrument Co., Ltd. specializes in high-pressure supercritical CO2 extraction systems and supercritical fluid extraction machines for pharmaceutical, food, and cosmetic industries. Founded in 2008, our equipment operates at up to 50 MPa, features full PLC automation, and achieves a CO2 recovery rate ≥95%. CE, ISO, UL, and SGS certified. OEM/ODM customization available with a 30-day lead time for custom orders.
50 MPa High-Pressure Safety System
Each unit integrates a quick-release safety interlock clamp, independent pump, and overvoltage safeguard. Structural integrity is validated by hydrostatic testing at 1.3×–1.5× maximum design pressure — documented and available for customer review.
Full PLC Automation
Automated isobaric and isothermal control keeps extraction parameters consistent batch after batch, reducing operator dependency and minimizing process deviation.
Flexible Multi-Stage Fractionation
Single, double, or triple-stage separators allow simultaneous collection of waxes, light oils, and heavy oleoresins in one continuous run — eliminating re-processing and additional equipment costs.
CO2 Closed-Loop Recovery
The integrated recirculation system recovers 95–98% of CO2 per cycle, directly reducing gas consumption costs and lowering environmental impact across long-term operation.
GMP-Grade Surface Finish
Product-contact surfaces are finished to Ra <0.8 μm, meeting GMP sanitary standards and minimizing cross-contamination risk between batches in pharmaceutical and food-grade production.
Step 1 — Pressurization
CO2 is compressed and heated past its critical point (31.1°C / 73.8 bar), entering a supercritical state where it combines the diffusivity of a gas with the solvating power of a liquid.
Step 2 — Selective Extraction
Pressure and temperature are tuned to target specific compounds. Lower settings favor volatile terpenes; higher settings extract heavier oleoresins and waxes.
Step 3 — Separation & Recovery
Pressure is released in staged separators, causing CO2 to return to gas and leaving behind a pure, solvent-free extract. The CO2 is then recaptured and re-pressurized for the next cycle.
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No
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MAIN CONFIGURATION
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REMARK
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1
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Extraction Tank
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Volume:5L+1L (2 tanks),Max working Pressure:50MPa
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2
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Separation Tank
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Volume:1X2L and 1X1L,Max working Pressure:30MPa
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3
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Pump
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CO2 high-pressure pump,Co-solvent pump
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4
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Cooling System
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Temperature range:-5℃~+5℃
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5
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Heating Exchange System
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Max working Pressure:50MPa
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6
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Purification System
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Max working Pressure:50MPa
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7
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CO2 Storage Tank
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Max working Pressure:16MPa
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8
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Flowrate Meter
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Model:Metal tube float (6.3-63L/H)
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9
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Temperature Control System
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Temperature Range: Room temperature~75℃
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10
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Safety Devices
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Pressure gauge at high pressure pump outlet,overpressureprotection The extractor, separator, evaporator, dry purifier and mixer have safety valve to keep safe of system.
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11
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User-supplied
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Power:3 phase,
CO2: Food grade≥99.5%, single bottle net weight ≥22Kg
Installation dimension: 2700×2500×1500mm
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Extraction vessels and all high-pressure components are manufactured from SS316L or SS304 stainless steel, meeting GMP sanitary and corrosion resistance requirements under continuous high-pressure cycling.
All circumferential welds undergo Non-Destructive Testing (NDT), including Radiographic (RT) and Ultrasonic (UT) inspection. Pressure vessels comply with ASME (U-Stamp) or PED standards based on your regional requirements.
Explosion-proof configurations are available for facilities operating with co-solvents in Class 1 Division 1 classified environments.
Pharmaceutical & Nutraceutical
Extract CBD, cannabinoids, Artemisinin, and botanical APIs at medical-grade purity. Validated extraction efficiency of 90–95% for targeted compounds (internal test data available upon request). No solvent residue, no heavy metal contamination.
Food & Beverage
Decaffeinate coffee and tea. Extract hop resins for brewing. The low-temperature process preserves heat-sensitive flavors and aromas that conventional high-temperature methods degrade.
Perfumery & Cosmetics
Extract essential oils from jasmine, rose, and other delicate botanicals without hydrolysis or oxidation of volatile terpenes, producing a true-to-nature scent profile that hydro-distillation cannot replicate.
Omega-3 & Carotenoid Concentrates
Produce omega-3 concentrates, lycopene, and astaxanthin from natural sources with high selectivity and minimal thermal degradation.
Our supercritical fluid extraction machines carry CE, ISO, UL, and SGS certifications and comply with GMP and FDA production standards. Certificate copies and audit reports are available upon request.
Every unit undergoes a Factory Acceptance Test (FAT) before shipment, validating PLC logic, safety interlocks, pressure relief systems, and weld integrity. Clients may attend in person at our Xi'an facility or receive full photo and video documentation for remote approval.
16+ Years of Dedicated Engineering
Founded in 2008, Xi'an Bioland Instrument has provided high-pressure extraction systems to 30+ countries in Europe, Southeast Asia, North America and the Middle East. In-house R&D for non-standard vessel volumes, specialised separator configurations and full manufacturing line integration.
Transparent Production Tracking
You're assigned a dedicated project specialist who sends weekly photo and video updates from fabrication to final inspection so you can see the process at every step.
Logistics Flexibility
We ship by sea, rail or air freight. We welcome OEM and ODM orders with confirmed lead times.
Tell us your target compound, throughput volume, and automation preference — we'll respond within 24 hours with a tailored proposal.
Q: What is the CO2 recovery rate?
A: The closed-loop system recovers and re-pressurizes 95–98% of CO2 per extraction cycle, based on internal operational data across standard botanical extraction runs.
Q: Can the machine operate in sub-critical mode?
A: Yes. Running at sub-critical pressure and temperature allows selective extraction of delicate volatiles and terpenes before transitioning to full supercritical parameters for heavier fractions.
Q: What facility infrastructure is required?
A: A stabilized 3-phase power supply, a chiller for CO2 condensation, and instrument air for pneumatic valves are required. If co-solvents are used, explosion-proof housing is mandatory.
Q: How does SFE compare to ethanol extraction in terms of efficiency?
A: SFE achieves 90–95% extraction efficiency for targeted compounds and eliminates post-processing steps required for solvent removal, reducing total processing time and contamination risk.
Q: How often do high-pressure pump seals need replacement?
A: Piston seals typically last 1,000–2,000 operating hours. Regular inlet filter maintenance and avoiding dry-run conditions can extend this interval.
Q: Can vessel size and separation stages be customized?
A: Yes. We support full OEM/ODM engineering. Customized units are typically completed within 30 business days after written specification confirmation.
Q: Do you provide installation support outside China?
A: On-site installation support is available internationally. Remote installation guidance via video call with technical documentation is the standard option included with every order.
If you want to get information about the supercritical fluid extraction machine, please contact us at info@biolandequip.com.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
