small co2 extraction machine

Small CO2 Extraction Machine for Lab & Boutique Production — Precision SFE System by Bioland

Xi'an Bioland has engineered supercritical fluid extraction systems for pharmaceutical labs, cannabis processors, and flavor houses for over 15 years. Our small CO2 extraction machines operate from 1L to 10L vessel volumes, reach up to 600 bar, and recover more than 95% of CO2 per cycle — giving boutique producers a clean, solvent-free extraction platform that scales with their process. Whether you are establishing DoE parameters for an API or running craft hemp batches, this system is built to match your precision requirements from day one. CE and ISO certified as standard; OEM/ODM accepted.

Key Features & Benefits

High-Pressure Architecture with Integrated Safety

Rated to 600 bar, the system handles high-molecular-weight lipids and hard-to-reach botanical compounds with consistent results. A quick-release clamp safety interlock prevents accidental depressurization. The independent plunger pump includes overvoltage protection and endurance-tested seals rated for 200–500 operational hours, depending on biomass type and run pressure.

Flexible Multi-Stage Separation

Single, double, or triple separators let operators target specific compound classes within a single run. Plant waxes drop out at an early stage; terpenes and cannabinoids collect in separate downstream vessels. The result is a fractionated extract ready for formulation — without a secondary winterization step at lower pressure settings.

Energy-Efficient Closed-Loop CO2 Recycling

An integrated molecular booster and condensation loop returns more than 95% of CO2 to the pump after each cycle. Reduced solvent consumption lowers operating costs and supports continuous production without frequent cylinder changes. For high-throughput boutique operations, this directly improves per-batch margins.

Full PLC Automation Available

The optional PLC panel automates pressure ramps, temperature holds, and valve sequencing. Temperature is held at ±0.5°C; pressure control stays within ±1% — both essential for maintaining consistent supercritical state conditions across repeated batches. Manual and semi-auto modes are also available for operators who prefer hands-on control.

How It Works?

Supercritical CO2 forms above 31.1°C and 73.8 bar. At this state, it combines the penetrating diffusivity of a gas with the solvating power of a liquid — entering plant matrices efficiently and carrying target compounds to the separator without residual solvent.

Pressure and temperature control polarity and selectivity. Running subcritical conditions below 31°C preserves volatile terpenes. Increasing pressure above 350 bar shifts selectivity toward cannabinoids, oleoresins, and lipids. This tunability gives operators a level of extract control that steam distillation and hydrocarbon solvents cannot replicate.

After extraction, CO2 pressure drops in the separator vessel. Target compounds precipitate into collection ports. CO2 vapor is then recondensed and returned to the high-pressure pump, completing the closed loop and minimizing waste.

Technical Parameters

Construction & Materials

All wetted components are manufactured from pharmaceutical-grade 316L stainless steel with internal Ra < 0.8 μm surface finishes, meeting GMP cleanliness requirements and preventing microbial retention between batches.

Every pressure vessel undergoes hydrostatic testing at 1.3× to 1.5× maximum operating pressure before leaving the factory. Helium sniff testing confirms hermetic sealing at all fittings and connections post-assembly. Calibration records for PID controllers are supplied with each machine, documenting temperature and pressure accuracy within validated ranges.

Replacement pump seals are stocked by our after-sales team. Customers receive a recommended maintenance schedule tailored to their biomass type and operating pressure at the time of commissioning.

Application Fields

Pharmaceutical R&D

Ideal for small-batch API extraction with full traceability. The system supports Design of Experiments (DoE) parameter development before scale-up, with zero residual solvent contamination — removing a significant regulatory concern for IND submissions and GMP audits.

Cannabis and Hemp Processing

Craft processors running subcritical parameters (below 31°C, low pressure) can harvest distinct terpene fractions for premium vape cartridges before decarboxylation. A small CO2 extraction machine gives boutique operators an extract quality standard that bulk industrial machines are not designed to achieve.

Natural Perfumery and Flavor Extraction

Heat-sensitive flowers — jasmine, rose, lavender — retain their "true-to-nature" aromatic profiles when extracted below thermal degradation thresholds. This is a critical requirement for luxury organic cosmetics and artisan fragrance formulations where steam distillation causes scorch damage.

Food and Nutraceuticals

Produce clean oleoresin spice extracts, decaffeinated ingredients, and omega-rich lipid fractions with no hydrocarbon solvent residues. Clean-label product positioning is fully supported, with extract documentation available for regulatory submissions.

Quality Certifications & Compliance

All units are manufactured under GMP-aligned production controls. PID calibration records and hydrostatic test reports are included in the documentation package shipped with every machine.

Services & After-Sales Support

Why Choose Bioland?

Over 15 years of in-house R&D and production means our engineering team has worked through the edge cases — high-pressure seal failures, biomass moisture variation, scale-up from 2L to 50L vessels — and those solutions are built into every standard unit we ship.

Each order is assigned a dedicated production specialist who sends weekly photos or videos as your build progresses. Before shipment, you receive a full documentation package and final inspection media for your sign-off. Factory Acceptance Testing (FAT) at our Xi'an facility is available for customers who need witnessed commissioning.

Logistics support covers sea, rail, and air freight. Every machine ships with a one-year full warranty and lifetime maintenance support backed by a stocked spare parts inventory.

FAQ

Q: What biomass load does this system handle per batch?

A: Vessel volumes from 1L to 10L support dried biomass loads of approximately 0.5 kg to 5 kg per batch, making the system well-matched to pilot runs and boutique production schedules.

Q: Can I run both subcritical and supercritical conditions on the same unit?

A: Yes. The thermal regulation system holds liquid CO2 states below 31°C for terpene-focused runs, and ramps to supercritical conditions above 31°C and 73.8 bar for broader compound extraction — all within the same hardware configuration.

Q: Is post-extraction winterization required?

A: Not necessarily. Running below 350 bar with multi-stage separator settings can reduce wax co-extraction to levels that eliminate a separate winterization step. Higher-pressure runs targeting full-spectrum extracts will typically still require winterization.

Q: What facility infrastructure is required?

A: A dedicated electrical circuit (3-phase recommended for chiller and heater loads), CO2 area monitoring alarms, and compressed air supply for pneumatic valves. Unlike hydrocarbon extraction systems, extensive explosion-proof room construction is not required.

Q: How often do pump seals need replacing?

A: Typically every 200–500 operational hours, depending on biomass cleanliness and sustained operating pressure. A maintenance log is recommended; replacement seals are available from our after-sales team with typically short lead times.

Q: Can you accommodate custom vessel sizes or non-standard pressure ratings?

A: Yes. OEM and ODM builds are accepted for custom vessel volumes, pressure ratings, automation configurations, and explosion-proof specifications. Contact us with your process parameters for a feasibility review.

Q: What is the typical quote turnaround time?

A: We respond to quote requests within 24 hours on business days. For custom builds, a preliminary proposal with lead time and pricing is issued within 48 hours after receiving your specification.

Request a Quote

Tell us your target compound, vessel size preference, and automation requirements for the small co2 extraction machine. Our team replies within 24 hours. Contact: info@biolandequip.com