Enterprise-level glass fractionating column systems made from quality borosilicate 3.3 glass are what XI'AN BIOLAND INSTRUMENT CO., LTD does best. Our columns are very good at separating things, and their HETP values are just right for cleaning up complex mixtures. These systems can work in temperatures ranging from room temperature to 300°C. They can achieve vacuum levels below 0.1mbar while keeping everything clear for real-time process tracking. Each unit has PID intelligent temperature control, customizable reflux ratios, and more than one packing choice. Capacity ranges from 5L to 100L. Our columns are approved by CE, ISO, UL, SGS, and ATEX, and they meet GMP/FDA standards for use in medicinal and food-grade settings. With changeable tower heights, heating methods, and material choices like SUS304/316L and titanium alloy, you get solutions that are perfectly suited to your needs, backed by more than 15 years of distillation experience.
Our product systems have full approvals from CE, ISO, UL, and SGS. Every unit follows GMP guidelines, which makes sure that your production meets the rules for the food and drug businesses.
Our in-house R&D team has been making chemical process equipment for more than 15 years and brings a lot of engineering experience to every job. We don't just sell tools; we also make custom plans to solve your separation problems.
Because it is made of clear glass, you can see the distillation, reflux, and liquid amounts in real time. This visual advantage helps you find problems and improve processes before they become expensive ones.
Need exact tower measurements? Different heating needs? Special fit with materials? We change everything about it to fit your exact process needs, from the volume and flow ratio to the type of packing and the pressure requirements.
It takes 5–7 days to ship standard setups. Made to order? Only 30 working days. We can ship your goods by sea, train, or air, and we'll find the fastest way to get them to you.
When you buy something, you get help with installation, training for the operator, and lifelong support for upkeep. A dedicated expert takes photos and movies every week of your equipment's production progress. Also, original extra parts are always in stock so they can be sent out right away.
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Model |
JLF-5S |
JLF-10S |
JLF-20S |
JLF-50S |
JLF-100S |
JLF-150S |
JLF-200S |
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Distillation Tank Volume |
5L |
10L |
20L |
50L |
100L |
150L |
200L |
|
Collection Tank Volume |
1L |
2L |
5L |
10L |
30L |
50L |
50L |
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Number of Collection Tanks |
1-4 sets (Customizable based on the number of fractions to be collected) |
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Stainless Steel Material |
304 Stainless Steel (Optional: 316 Stainless Steel) |
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Heating Tank |
Oil bath heater or jacket with heating liquid circulation |
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Distillation Tower Height |
Height can be customized according to the required number of theoretical plates |
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Distillation Tower Diameter |
40mm, 50mm, 80mm, 100mm or other customizable sizes |
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Distillation Tower Heating (Optional) |
Heating jacket or heating belt |
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Stirring Mode |
Magnetic stirrer, magnetic rotating stirrer or top/head stirrer (magnetic seal or mechanical seal) |
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Operating Temperature Range |
Room temperature to 300°C |
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Control System |
Digital display stirring speed controller, timer for reflux receiver/distributor, heating jacket or heating temperature controller. For oil bath heating, an additional heating temperature controller is required. |
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Accessories (Optional) |
Cooling circulator for condenser; Heater for jacketed distillation tank; Vacuum pump |
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Power Supply |
220V or 380V, 50/60HZ |
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The first thing you have to separate is a liquid mixture with parts that boil at different temperatures. This is how our method makes sure purity:
It gets warmer in your generator, which makes the mixture vaporize. Ascending vapour is made when parts with lower boiling points evaporate first.
Multiple Stages of Contact: As the vapour rises through the column, it comes into contact with packing material or surfaces that are organized. This makes a huge number of tiny areas where vapour can cool down and condense partly.
Continuous Refinement: As new vapour rises, the collected liquid moves downhill and meets it. This exchange against the flow of current creates a balance between vapour and liquid at several possible plates inside the column.
Selective Condensation: Components that heat faster tend to condense and return to the jar. Lower-boiling parts keep going up, and each stage makes them purer.
Controlled Reflux: Some of the collected vapour that is at the top of the column flows back down (reflux), while the rest gathers as a clean product. This ratio is controlled to find the right mix between purity and output.
Real-Time Observation: The clear glass walls let you see phase changes, flooding signs, and how the liquid behaves, so you can make changes to the process right away.
With this design, single-pass distillation is turned into a complex series of cleaning steps that separate parts whose boiling points are as close as 2°C apart.
1. Get the system ready by connecting the vacuum pump, heating system, and reactor. Install the right packing material for your blend based on its features.
2. Adding the combination: Use the charge port to add your liquid combination to the reactor vessel.
3. Programming the temperature: Use the PID device to set the values you want. During the run, the device keeps accurate thermal maps.
4. Vacuum Application (Optional): For materials that break down easily in heat, use vacuum to lower their boiling points and stop thermal decline.
5. Heating Initiation: Turn on the heating method you picked. As the first vapours start to rise, keep an eye on the clear column.
6. Set up the reflux: Change the ratio of reflux as the vapour hits the top of the column. When the rates are low, the output goes up and the purity goes up.
7. Collection of Fractions: Gather clean fractions at set temperature plateaus. The clear design makes it easy to see when each fraction changes.
8. Continuous Monitoring: Keep an eye on the column to make sure it works right. Right away, you can see flooding, channelling, or rushing through the glass walls.
9. Process Optimization: Change factors in real time based on data from the temperature and what you see.
10. Completion and Recovery: Once all the fractions you want have been collected, cool the system down safely and get back any leftover material.
Cleanse Active Pharmaceutical Ingredients (APIs) and sort structure isomers without letting metals get in the way. The glass surface is neutral, which meets GMP standards and provides the high purity needed for drug manufacturing and pharmaceutical intermediates.
Citrus oils should be gently deterpenated, and aromatic chemicals should be concentrated under a vacuum. Keep delicate smell profiles while getting rid of unstable parts that shorten the product's shelf life.
Do studies on fuel mixture and analyzing crude oil. Recreate the conditions of a refinery tower while keeping an eye on the areas where hydrocarbons separate and improving reflux tactics.
Sort out complicated chemical mixes, clean up specialized solvents, and separate out high-value intermediates. Our structure makes it safe to work with materials that are acidic or basic.
Make booze that is safe for food, flavour concentrates, and natural extracts. With our FDA-compliant products and contamination-free distilling, you can meet strict safety standards.
Refine botanical extracts, isolate active ingredients, and create concentrated essences for high-end formulations without introducing impurities.
Develop new processes, test separation parameters, and scale up from bench to pilot production using equipment that mirrors industrial systems.
The fact that our factory has a lot of quality certifications means that your tools will meet foreign standards:
Before it is shipped, every glass fractionating column goes through strict quality control checks, such as polariscopic stress analysis, vacuum integrity testing, joint precision measurement, and internal shape verification.
Q: What's the difference between a product and simple distillation?
A: Simple distillation performs one vaporization-condensation cycle, suitable only for components with widely different boiling points (>25°C difference). Our columns provide multiple theoretical plates through packing or structured surfaces, enabling separation of mixtures with boiling points as close as 2°C. You get dramatically higher purity in a single run.
Q: Can I use this equipment with corrosive chemicals?
A: Absolutely. Borosilicate 3.3 glass offers excellent resistance to most acids, alkalis, halogens, and organic solvents. For extremely aggressive materials, we offer SUS316L or titanium alloy construction options.
Q: How do I choose the right capacity?
A: Consider your batch size and throughput requirements. For laboratory R&D, 5–20L typically suffices. Pilot production often needs 30–50L. Industrial applications may require 100L or larger custom systems. Our team can help you calculate the optimal size based on your specific process.
Q: What maintenance does the equipment require?
A: Regular inspection of ground glass joints, replacement of packing material as it degrades, and cleaning between different mixtures. We provide detailed maintenance protocols and keep original spare parts in stock. Our lifetime maintenance support ensures you're never without technical assistance.
Q: Can you customize the column for vacuum distillation?
A: Yes. Our systems routinely achieve vacuum levels below 0.1mbar. We can customize joint sealing, vacuum port placement, and pressure monitoring based on your specific requirements for heat-sensitive compound purification.
Q: What heating method works best for my application?
A: Electric heating offers precise control for laboratory use. Heat transfer oil provides uniform heating for larger batches. Steam heating suits continuous industrial operations. Share your process details, and we'll recommend the optimal configuration.
Q: How long does customization take?
A: Standard models ship in 5–7 business days. Custom configurations typically require 30 business days from design approval to completion. We document your equipment's progress weekly, so you're always informed.
Q: Do you provide installation and training?
A: Yes. We offer comprehensive installation guidance, operator training, and ongoing technical support. Your investment includes the knowledge transfer needed to maximize equipment performance and longevity.
Ready to enhance your separation capabilities with glass fractionating column? Contact our technical team today at info@biolandequip.com for customized solutions, technical specifications, or quotations.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
