With its advanced intermediate thermal separation system, Xi'an Bioland Instrument's pilot scale spray dryer is designed to bridge the gap between R&D in the lab and full-scale commercial production. This equipment can evaporate between 5L/h and 25L/h, so it can accurately simulate conditions on a production scale. Inlet temperature control from 120°C to 350°C with PID accuracy of ±1°C, dual-mode atomization (centrifugal up to 30,000 RPM and two-fluid nozzles), and product-contact surfaces made from SS316L stainless steel with a mirror-polish finish (Ra < 0.4εm) are some of the features of our product. It is made for materials that are sensitive to heat and can dry instantly at temperatures as low as 40–60°C, ensuring that 92–98% of the powder is recovered.
Xi'an Bioland Instrument brings over 15 years of specialized experience in chemical process equipment. We're not just suppliers—we're your technical partners.
It's important that you feel calm. We are licensed by CE, ISO, UL, and SGS. All of the equipment we use meets GMP/FDA guidelines, which means it is legal to use in food and drug uses.
Not every process is the same. Our in-house research and development team creates tools and production lines that are exactly what you need. Please feel free to use our OEM/ODM services.
It takes 5–7 work days to ship standard items. Unique answers? Only 30 working days. To meet your deadline, we can help with freight by sea, train, and air.
Every step of the way, you are kept in the loop. Our hardworking specialists give you weekly reports on your progress with pictures or videos. You decide when the final inspection takes place—remotely or at our facility during Factory Acceptance Testing.
We offer a quality guarantee for one year and upkeep for life. Our highly trained expert team will make sure you get the most out of your investment from the time it is installed until it is used.
|
Item |
BL-S15 |
BL-5000 |
BL-10L |
BL-25L |
BL-50L |
BL-100L |
|
inlet temperature(℃) |
140-350 automatically controlled |
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|
outlet temerature (℃) |
~80-90 |
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|
Max.water evaporation capacity(L/h) |
2 |
5 |
10 |
25 |
50 |
100 |
|
centrifugal spraying nozzle transmission mode |
compressed air transmission |
Mechanical transmission |
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|
Rotation speed rpm |
25000 |
18000 |
18000 |
18000 |
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Nozzle diameter mm |
0.5mm, 0.7mm, 1mm, 1.5mm, 2mm are available for selection |
50mm |
80mm |
100mm |
120mm |
140mm |
|
Nozzle type |
Two fluid nozzle |
High speed Centrifugal atomizer |
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|
Heat supply |
Electricity |
Electricity+steam |
Electricity+steam,fuel oil or gas |
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|
Max.Electric heating power kw |
3.5 |
9 |
15 |
36 |
63 |
81
|
|
Dried powder restoring tate % |
≥95 |
≥95 |
≥95 |
≥95 |
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The working idea is simple but complex at the same time.
The liquid feed first comes in through a precise pump. Either a high-speed spinning disc or a pressure nozzle atomization system breaks the liquid into tiny drops.
The drops hit the hot air that is moving through the drying room. Instantaneous evaporation happens when the particles lose water very quickly.
Temperature sensors constantly check the air coming in and going out. The PLC system changes the hot parts to keep the drying conditions just right.
As air moves lower, dried bits move with it. Powder is easily collected by the separation device, which is usually a cyclone with bag filters.
Lastly, your product is put together in the right packages. Filtration systems let clean waste air out, which is required by the environment.
For uses with solvents, a closed-loop nitrogen device lowers the risk of explosion. Oxygen detectors keep an eye on levels below 2% and stop automatically as a safety measure.
Step 1: Feed Preparation → Prepare your liquid slurry or solution with desired solid content and viscosity.
Step 2: Parameter Setting → Configure inlet/outlet temperatures, feed rate, and atomization speed via touchscreen.
Step 3: System Preheating → The heating system reaches target temperature with precise PID control.
Step 4: Atomization → Feed pump delivers liquid to the atomizer, creating uniform droplets.
Step 5: Drying → Hot air contacts droplets, instantly evaporating moisture while preserving product properties.
Step 6: Separation → Cyclone and bag filters separate dried powder from exhaust air.
Step 7: Collection → Collect high-purity powder with minimal loss.
Step 8: CIP Cleaning → Sanitary Tri-Clamp connections enable easy cleaning between batches.
You need an exact range of particle sizes for APIs, pilot scale spray dryer right? This equipment works great in clean rooms. It makes powders and pellets that can be breathed in and have controlled release qualities. Bioavailability stays the same from one batch to the next.
It becomes very easy to turn liquid emulsions into stable powders. Essential oils, oleoresins, and fruit drinks with a lot of sugar were all handled well. Cooled-wall technologies stop sticky materials from sticking to the walls. The flavour stays strong. The shelf life gets a lot longer.
Making cathode compounds for lithium-ion batteries? Ceramics with zirconia? The method works well with both rough slurries and organic fluids. It gives you spherical pellets with a high density that are great for isostatic pressing. Solvents like acetone or ethanol can be safely recovered by nitrogen-inerted loops.
Biologics that are sensitive to heat need to be handled carefully. Drying at low temperatures (40–60°C) keeps enzyme function and protein structure.
Consistent particle shape makes processing and product performance better for everything from catalysts to specialty chemicals.
Xi'an Bioland Instrument maintains rigorous quality standards:
Our quality control includes:
Material Traceability: SS316L makeup has been approved by PMI tests. Use a profilometer to make sure the surface finish meets the standards for pharmaceuticals.
Factory Acceptance Testing: Before shipping, we check the rate of loss, the heater's performance, and all the safety interlocks.
Atomizer Balancing: Vibration research makes sure that the atomizer works smoothly at high speeds.
Seal Integrity: Testing for vacuum decay makes sure that the seal is airtight for closed-loop liquid processing.
IQ/OQ Documentation: The installation and operation qualification processes meet the requirements of FDA 21 CFR Part 11 for businesses that are regulated.
Q1: How accurately does data scale up to production?
The product provides over 95% correlation. Geometric similarity and identical residence times to production towers ensure reliable thermal efficiency calculations and particle morphology predictions.
Q2: Can the system prevent cross-contamination?
Absolutely. Premium models feature sanitary Tri-Clamp connections and integrated CIP spray balls. Complete disassembly and cleaning validation takes under 2 hours.
Q3: How do you handle organic solvents safely?
We utilize explosion-proof closed-loop systems with nitrogen inerting. Oxygen analyzers maintain O2 levels below 2% with automatic safety shutdown.
Q4: What yield can I expect for high-value products?
High-efficiency cyclones and secondary bag filters with pulse-blowback typically achieve 92-98% recovery yields—far superior to laboratory units.
Q5: Can it process high-viscosity feedstocks?
Yes. With appropriate progressive cavity pumps and proper nozzle selection, it handles viscosities up to 1000 cps depending on material properties.
Q6: What's included in your warranty?
You receive a one-year quality warranty with lifetime maintenance support. Our technical team remains available for troubleshooting and optimization.
Q7: Do you provide installation training?
We offer comprehensive training—either at your facility or ours. Your operators will understand every aspect of operation and maintenance.
Ready to scale up your process with pilot scale spray dryer with confidence? Contact our technical team today at info@biolandequip.com for customized solutions and expert consultation.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
