That's exactly what our Crystallization Filter Reactor from Xi'an Bioland Instrument does. This enterprise-grade system works smoothly from -80°C to 250°C and has a temperature control accuracy of ±0.1°C. It was made by people who have been making things for over 15 years. The machines have PTFE sandcore filtration, PLC control choices, and designs that keep them from exploding. It meets all GMP and FDA guidelines and has been approved by CE, ISO, UL, and SGS. This three-in-one method gets rid of the need to move materials between different tanks, which lowers the risk of contamination and raises the output. When you buy directly from the plant and get OEM/ODM solutions that are made to fit your process needs, you save a lot of money on your production costs.
The Crystallization Filter Reactor is a commonly used biochemical instrument, which combines the functions of the reactor and the filter. It suitable for the chemical reaction and physical process under the synthesis, catalysis or other solid liquid of the laboratory / factory, so that one or more steps can be carried out in the same kettle (such as filtration after the completion of the reaction), thus reducing the drift of material measurement and reducing the transfer times of the reaction substrate. It is used in such fields as pharmaceuticals, peptide synthesis, tobacco research and so on.
It's widely used in pharmaceutical and chemical industries, especially in drug synthesis, fine chemical industry, petrochemical process, new material synthesis, concentration, crystallization and other experiments.
1. The controller box is imported and easy to operate, digital display speed and temperature
2. Option filter plate, pore size from 0.1 to 200μm
3. All glass is GG17 borosilicate glass
4. Filter board can easy removeable
5. PTFE paddle or glass paddle for clients' option
6. PTFE bottom value with no dead angle design
7. PTFE discharge valve, discharge completely and quickly, no leak/pollution to the solvent.
8. PTFE and special rubber compound seal, can withstand different solvents and maintain high vacuum degree.
9. Stainless steel bracket system, easy to disassemble
10. Customized service according to customers' needs
Why Choose Us?
If you choose Xi'an Bioland Instrument, you'll be working with a company that knows how hard it is for you to make things.
Quality You Can Trust
We have certificates from CE, ISO, UL, and SGS that are known all over the world in the chemical and pharmaceutical businesses. Before it is shipped, every reactor goes through a strict quality check.
Expert Engineering Team
Years of experience creating unique filtration and crystallization systems are what our R&D staff brings to the table. We offer full process solutions, not just tools sales.
Transparent Production Tracking
During production, our specialized expert sends weekly progress reports with photos or videos that show the work in detail. You are kept in the loop at all times until the final decision.
Fast Delivery Options
Units that aren't modified take 5–7 days to ship. Systems that are made just for you are delivered within 30 business days. To meet your deadline, we can help with freight by sea, train, and air.
Comprehensive After-Sales Support
You can get a quality guarantee for one year and upkeep services for life. Our technical support team gets back to you quickly to make sure your business keeps running smoothly.
Cost-Effective Factory Direct Sales
We offer reasonable pricing because we cut out the middlemen. This means that your R&D and pilot-scale funding costs will be much lower without sacrificing quality.
|
MODEL |
BL-FR10L |
BL-FR20L |
BL-FR30L |
BL-FR50L |
BL-FR100L |
|
Material capacity |
10L |
20L |
30L |
50L |
100L |
|
Jacket capacity |
≈2L |
≈5L |
≈8L |
≈15L |
≈20L |
|
Receiving flask |
5L |
10L |
10L |
20L |
20L |
|
Reactor body and cover |
Apply vacuum grease to the connection surface between the upper part of the kettle body and the kettle cover. |
||||
|
Variable-frequency governor |
Digital temperature and rotate speed |
||||
|
Rotate speed |
0-300r/min |
||||
|
Seal |
Self-lubricating mechanical seal |
||||
|
Filter base plate |
PTFE filter sand core |
||||
|
Bore diameter of sand core |
1-200μm (Optional) |
||||
|
Motor power |
120W/1:3 |
200W/1:3 |
|||
|
Power of explosion-proof motor |
180W |
370W |
370W/1:3 |
||
|
Voltage |
220V/50Hz which can be customized according to customer requirements |
||||
Application Fields
Your business needs equipment that is effective and meets strict standards for safety and purity.
Pharmaceutical Manufacturing
Perfect for isolating clean APIs, making antibiotics, and crystallizing drugs for cancer. The closed system keeps the operators from coming into contact with high-potency substances and follows cGMPs throughout the whole process.
Fine Chemical Production
Deals with harsh chemicals and high temperatures to make complex organic intermediates. The reactor does reaction and separation one after the other without putting workers in contact with dangerous vapours.
Peptide Drug Development
Put to good use in peptide research and development and thymic peptide preparation. Accurate temperature control and a clean setting make sure that sensitive biomolecule crystallization results can be repeated.
Agrochemical Synthesis
Handles herbicide intermediates that need to be separated into solids and liquids right away after the process is done. Within the closed system, catalyst recycling works well and is safe.
Botanical Extraction
Used a lot in the steps of isolating CBD and storing it for the winter. In one tank, the unit cools ethanol mixtures to crystallize fats that aren't wanted, screens them out, and then gets the solvent back.
New Materials Development
Applicable to specialty pigments, optical brighteners, and electronic chemical production where particle size distribution directly impacts material properties.
Chemical Intermediates
Proven in antimicrobial peptide screening and other high-standard production lines requiring strict quality control and batch-to-batch consistency.
Xi'an Bioland Instrument maintains comprehensive quality management systems recognized internationally:
All materials used in construction come with full traceability documentation and material certificates.
Q: Can your reactor handle extremely low temperatures for cryogenic crystallization?
A: Absolutely. Our system supports temperatures down to -80°C with specialized refrigeration jackets, perfect for thermally sensitive compounds requiring cold crystallization.
Q: How do you prevent filter cake cracking during the drying phase?
A: The raking agitator rotates and lowers simultaneously, smoothing and compressing the cake surface. This prevents gas channeling and ensures uniform drying throughout the entire bed.
Q: Is the equipment suitable for explosive solvents like hexane or acetone?
A: Yes. We offer ATEX-certified explosion-proof configurations with inert gas purging systems that maintain oxygen levels below the Lower Explosive Limit for complete safety.
Q: What's the lifespan of the sintered metal filter plate?
A: Unlike disposable cloth filters, our multi-layer metal mesh plates last several years. They're designed for back-flushing and ultrasonic regeneration without requiring disassembly.
Q: Can you customize the reactor for our specific process requirements?
A: Certainly. We provide full-dimension non-standard customization including vessel dimensions, material selection, agitator types, temperature ranges, and integrated modules like ultrasonic crystallization or distillation systems.
Q: How do you prevent cross-contamination between different product batches?
A: The one-pot design eliminates transfer piping between separate machines—a common contamination source. Additionally, automated CIP/SIP systems thoroughly clean and sterilize all internal surfaces between batches.
Q: What documentation do you provide for regulatory compliance?
A: We supply complete material certificates, pressure vessel certification, electrical safety documentation, FAT reports, and operation/maintenance manuals meeting international regulatory requirements.
Ready to optimize your crystallization process with a Crystallization Filter Reactor? Our technical team is here to help design the perfect solution for your production needs. Reach us at info@biolandequip.com today!
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.
