Jacketed Filter Glass Reactor - Professional Laboratory & Pilot-Scale Solution
Xi'an Bioland Instrument Co., Ltd. offers enterprise-grade jacketed filter glass reactor systems that combine reaction, crystallization, and filtering. Our reactors, made of high borosilicate glass 3.3, eliminate material transfer losses and contamination with accurate temperature control from -80°C to 250°C. A completely visible process solution is achieved with certified explosion-proof solutions, PLC automation, and PTFE, stainless steel, and titanium filtering. CE, ISO, UL, and SGS-certified systems fulfill GMP/FDA requirements. Factory-direct cost includes lifetime maintenance and 30-day bespoke manufacture and 5–7-day standard model delivery.

Product Description
The jacketed glass reactor with integrated filtration streamlines multiple unit operations. The double-wall jacket circulates heat transfer fluids for accurate thermal control and the bottom-mounted filter plate separates solids and liquids immediately.

Key Features:
- High-borosilicate glass 3.3 resists acids, alkalis, and organic solvents.
- Transparent design allows real-time crystallization dynamics observation.
- Filter plates with PTFE coating and 10–100µm ratings can handle various particle sizes.

- Long-lasting German-imported seals with FFKM O-rings
- Adjustable anchor, paddle, or turbine impellers for variable-frequency stirring

- PID temperature control ±0.1°C precise.
- Options include electric lifting, PLC automation, and explosion-proof systems.
Dead-space elimination and turbulent jacket flow increase heat exchange in your process. The modular design integrates ultrasonic crystallization, distillation columns, and vacuum systems.

Why Choose Xi'an Bioland Instrument?
Excellence in Manufacturing for 15+ Years
Chemical process equipment, distillation, extraction, and reaction systems are our specialties.
Comprehensive Certifications
Our quality is certified by CE, ISO, UL, SGS, ATEX, and IEC. All equipment meets GMP/FDA standards.

Full-Spectrum Customization
We design vessels and stirring systems to meet your process needs. OEM/ODM services provide peptide synthesis, chemical intermediates, and botanical extraction.
Transparent Production Tracking
Your specialist updates photos and videos weekly during manufacture. Pre-shipment FAT is performed in our facilities.
Competitive Factory-Direct Pricing
Remove distributor markups. R&D and pilot-scale investment expenditures are greatly reduced by direct sales.
Responsive After-Sales Support
One-year warranty, lifelong maintenance. Engineering helps with installation, training, and troubleshooting.

Technical Parameters
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MODEL
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BL-FR10L
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BL-FR20L
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BL-FR30L
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BL-FR50L
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BL-FR100L
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|
Material capacity
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10L
|
20L
|
30L
|
50L
|
100L
|
|
Jacket capacity
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≈2L
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≈5L
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≈8L
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≈15L
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≈20L
|
|
Receiving flask
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5L
|
10L
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10L
|
20L
|
20L
|
|
Reactor body and cover
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Apply vacuum grease to the connection surface between the upper part of the kettle body and the kettle cover.
|
|
Variable-frequency governor
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Digital temperature and rotate speed
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|
Rotate speed
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0-300r/min
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|
Seal
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Self-lubricating mechanical seal
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|
Filter base plate
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PTFE filter sand core
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|
Bore diameter of sand core
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1-200μm (Optional)
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|
Motor power
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120W/1:3
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200W/1:3
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|
Power of explosion-proof motor
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180W
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370W
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370W/1:3
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|
Voltage
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220V/50Hz which can be customized according to customer requirements
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Working Principle
The jacketed filter glass reactor operates through coordinated thermal and mechanical processes:
1. Thermal Management
Thermal fluid flows through the double-wall jacket. Optimized jacket shape increases turbulence and heat exchange. Rapid heating or controlled cooling ramps enable crystallization.
2. Reaction Phase
Glass vessel reactants mix while stirring preserves homogeneity. Transparent walls show colour changes, phase separations, and precipitation in real time.
3. Crystallization Control
Programmable temperature lowering influences nucleation and crystal growth. Cooling slowly generates bigger crystals; cooling quickly produces tiny particles. Set cooling rate to achieve crystal size dispersion.
4. Integrated Filtration
Apply vacuum through the bottom valve after reaction. While solids stay in the jar, mother liquid drains through the filter plate. Lack of material transfer eliminates yield losses.
5. Washing & Drying
Washing the filter cake with fresh solvent from the top. Multi-wash cycles occur in-situ. Finally, the jacket heats solvent evaporation under vacuum for dry product.

Application Fields
Pharmaceutical & Biotechnology
Solid-phase peptide synthesis requires many reaction and filtering cycles. The jacketed filter reactor prevents peptide degradation by holding resin beads throughout washing, coupling, and deprotection.
Fine Chemical Crystallization
Control crystal morphology and produce high-purity intermediates. The transparent tank permits polymorph screening and integrated filtration protects sensitive crystal structures.
Cannabis & Hemp Processing
Chilled ethanol dissolves crude extract during winterization. Fats and waxes precipitate at low temperatures. Wax doesn't dissolve again since the cool jacket keeps the temperature down during filtering.
New Materials Research
Where metallic pollution degrades products, synthesize graphene oxide or nanoparticles. Inert touch surfaces are guaranteed by glass.
Chemical Intermediate Production
Visual process monitoring and improved workflow decrease contamination hazards in specialized chemical batch manufacturing.
Quality Certification
Xi'an Bioland Instrument maintains rigorous quality standards:
- CE certification confirms that the product meets European health and safety standards
- ISO 9001 is a certification for a quality management system.
- UL Listing: Meeting North American safety standards
- SGS Verification: Validation of a third-party quality review
- Explosion-Proof ATEX/IEC: Not required in dangerous areas
- GMP/FDA Compliance: The design and output meet the standards for drugs.
Before it is shipped, every tank is put through pressure tests, leak checks, and performance checks. Material certificates, test records, and operation instructions are all part of documentation packages.
FAQ
Q: What is the maximum thermal shock your product can handle?
A: Borosilicate glass 3.3 tolerates a Delta T of approximately 50–60°C for larger jacketed vessels. We recommend gradual temperature ramping to prevent thermal stress fractures and extend equipment lifespan.
Q: How do you clean a clogged filter plate?
A: Three methods work effectively: (1) Back-flush solvent through the bottom valve upward. (2) Remove and ultrasonically clean the plate if your model allows. (3) Use compatible chemical digestion for stubborn organic residues, ensuring seal material compatibility.
Q: Can this reactor handle positive pressure for filtration?
A: Glass vessels primarily operate under vacuum. However, they typically withstand low positive pressure (max 0.5 bar or 7 psi) to assist filtration. Exceeding this creates safety risks. Always verify your specific pressure rating.
Q: Is the PTFE filter plate compatible with all solvents?
A: PTFE resists nearly all industrial chemicals. Confirm that supporting structures (PEEK or PP) and O-rings (Viton vs. FFKM) match your solvent's compatibility profile, particularly with aggressive ketones or ethers.
Q: What seal types maintain high vacuum?
A: We use dynamic mechanical seals or magnetic coupling drives. For vacuum levels below 10 mbar, double mechanical seals with barrier fluid prevent lubricant contamination and maintain process integrity.
Q: What are standard delivery times?
A: Custom configurations require approximately 30 business days. Standard models ship within 5–7 days. We accommodate urgent requests when possible.
Q: Do you provide installation and training?
A: Yes. Our technical team offers on-site installation guidance, operator training, and process optimization support as part of our comprehensive service package.
Contact Us
Ready to enhance your laboratory efficiency with a jacketed filter glass reactor? Reach our team at info@biolandequip.com to discuss your specific requirements and receive a customized quotation today.