50L Rotovap for Sale: The Ultimate Guide to Large-Scale Solvent Evaporation Solutions
Why 50L Rotovaps Are Indispensable Across Industries
The 50L Rotovap is a large capacity rotary evaporation equipment designed specifically for pilot production and industrial scale, widely used in concentration, crystallization, drying, separation, and solvent recovery processes in industries such as pharmaceuticals, chemicals, biopharmaceuticals, food, cosmetics, etc.
The RE-50L model 50L rotary evaporator adopts an EL airtight system and a main and auxiliary high-efficiency dual condenser design to achieve efficient evaporation and recovery of solvents under vacuum conditions. The evaporation efficiency is 3-5 times higher than traditional methods, making it particularly suitable for low-temperature concentration and purification of thermosensitive biological products

Working principle: Core mechanism of rotary evaporation technology
The 50L Rotovap rotary evaporator is based on the principle of vacuum distillation and achieves efficient evaporation through the synergistic effect of the following three core elements:
Element action mechanism, technical effect, vacuum pressure reduction system can seal and reduce pressure to 400-600 mmHg to lower the boiling point of the solvent, achieve low-temperature evaporation, constant temperature heating, water bath, electronic constant temperature control (room temperature -200 ℃), accurately control the evaporation temperature, prevent thermal decomposition from rotating into a film. The flask rotates at a constant speed (0-120 rpm), and the material forms a large thin film on the bottle wall, increasing the evaporation area

Workflow:
1.The rotating bottle is placed in a constant temperature water bath in a vacuum state
2.The motor-driven flask rotates at a constant speed, and the solution forms a uniform thin film on the bottle wall
3.Rapid evaporation of solvents under negative pressure and heating conditions
4.Steam is cooled and liquefied by an efficient condenser
5.Recycling in collection bottles to achieve solvent separation and recovery

Core functional features
1.EL airtight system
Adopting the internationally advanced EL airtight system, combined with Teflon (PTFE) and fluororubber dual rotary seals, to ensure high vacuum retention, gas-liquid separation without reflux, and maximizing evaporation efficiency.
2.Design of main and auxiliary dual condensers
The main condenser is responsible for the main steam condensation, and the auxiliary condenser serves as an auxiliary condenser to ensure high recovery rate, especially suitable for the recovery of low boiling point solvents.
3.Vacuum switching valve
A vacuum check valve is installed between the condenser and the collection bottle, which does not affect the evaporation vacuum during discharge, enabling continuous feeding and collection, and improving production efficiency.
4.PTEE discharge valve
The collection bottle is equipped with a PTFE discharge valve at the bottom, which is corrosion-resistant and pollution-free. The recovery of solvents is very fast, avoiding solvent residue and cross contamination.
5.Intelligent temperature control system
The electronic constant temperature control of the water bath pot has small temperature fluctuations, more stable evaporation, less material flushing, no spark control, and is safe and reliable.

6.Bottle return device
The rotating bottle adopts ISO29 standard mouth, which can be easily removed with threads to reduce glass damage and solve the problem of difficult bottle removal under high temperature.
7.Vertical condenser configuration
Strong maneuverability, with three options available. Equipped with a cold trap for low boiling point evaporation collection, it can adapt to the condensation needs of different solvents.
8.Security protection system
The lifting of the constant temperature bath and protective cover relies on an electronically controlled hydraulic system
Automatically lower the boiler when power is cut off, door is opened, or overheating occurs
Brake disc protection glassware to prevent sudden overpressure

Main technical parameters
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Product Model
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RE-5L
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RE-10L
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RE-20L
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RE-50L
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Glass Assembly
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Material
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(GG17) Borosilicate glass 3.3
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|
Carafe(L)
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5L
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10L
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20L
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50L
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|
Collection Bottle
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3L
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5L
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10L
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20L +10L
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|
Condensers
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Framework
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Double Vertical
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|
Device
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Rotary motor
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Controllers
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DC infinitely variable speed control
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Number of Revolutions Per Minute
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20~150r/min
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20~140r/min
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20~140r/min
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20~120r/min
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|
Bathtub
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Power(KW)
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2
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3
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4
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6
|
|
Temperature Control Range(℃)
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ordinary temperatures+5~200
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|
Lifting Method
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Electric bath lift
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|
Size of the Whole Machine(mm)
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800W×420D×1100H
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1050W×580D×1750H
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1150W×650D×1900H
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1280W×700D×2200H
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|
Power Requirement
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220V/50Hz
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Practical case sharing
Concentration of Biopharmaceutical Fermentation Liquid
Client: Biopharmaceutical Company
Application: Concentration of antibiotics in fermentation broth
Challenge: Large fermentation broth volume, strong thermal sensitivity, requiring low-temperature concentration
achievements:
Antibiotic activity retention rate: 94%
Concentration factor: 10 times
Solvent recovery rate: 96%
Production cycle shortened: 60%

Chemical solvent recovery
Customer: Fine chemical enterprise
Application: Recovery and reuse of organic solvents
Challenge: Mixing multiple solvents with high purity requirements for recycling
economic performance:
Annual solvent recovery: 500 tons
Cost savings: approximately 1.2 million yuan per year
Environmental benefits: Reduce VOCs emissions by 80%
Applications of 50L Rotovaps
A 50L Rotovap for sale is versatile across industries:
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Pharmaceuticals: Concentrating drug extracts, purifying active ingredients, solvent recovery in GMP-compliant environments.
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Chemical Research: Isolating reaction products, removing solvents from intermediates, scaling up synthesis processes.
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Food & Beverage: Concentrating fruit juices, extracting essential oils, removing water from natural products.
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Cosmetics: Purifying active ingredients, concentrating herbal extracts, solvent recycling in production.
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Environmental Testing: Analyzing pollutants in large water samples, concentrating organic compounds for GC/MS analysis.

Final Thoughts: Invest in a 50L Rotovap for Long-Term Efficiency
A 50L Rotovap for sale is more than a lab tool—it’s a productivity booster for industries reliant on large-scale solvent processing. Whether you need to cut processing time by 50% or reduce solvent waste through efficient recovery, a 50L Rotovap delivers ROI through speed, precision, and scalability.
Ready to upgrade your lab or production line? Compare models, request quotes, and choose the 50L Rotovap for sale that aligns with your volume, budget, and technical needs. Don’t let manual evaporation slow you down—embrace automation and efficiency today! -info@biolandequip.com