The continuous flow ultrasonic reactor from Xi'an Bioland Instrument provides high-quality acoustic cavitation processes for chemical, medicinal, and biotechnology uses. In either a single-pass or recirculating setup, our device forces your whole product stream through a small cavitation zone. This makes sure that each flowing part gets the same amount of specific energy. When the PDI is less than 0.2, the particle size consistently decreases, and reaction times are cut in half. Our reactor lowers the working temperature by 20–30°C to protect chemicals that are sensitive to heat. It works at a frequency of 20–30kHz and has ultrasonic power that can be adjusted from 250W to 4000W. The system is made of high-borosilicate glass or SUS316L and has titanium metal needles. It fully meets GMP/FDA standards and has been certified by CE, ISO, UL, and SGS.
continuous flow ultrasonic reactor is an instrument for ultrasonic treatment of substances by using the cavitation effect of ultrasonic waves in liquid. It is composed of ultrasonic generator, transducer, amplifier rod and reaction kettle body. The generator produces high-frequency electrical signals, the transducer converts the electrical signals into mechanical vibration, the amplifier rod amplifies the vibration amplitude, the reaction kettle body holds the material, and through the coordinated work of these parts, it realizes the processing of the material's crushing, emulsifying and separating.
1.The whole stainless steel column, mobile framework, 4-6 or more covers of the reaction kettle, with full set of glass parts for reflux, adding liquid, temperature measurement, and so on.
2. Use G3.3 high borosilicate glass, with good chemial and physical properties.
3. Alloy steel mechanical seal, PTFE connector, to maintain a high precision seal in the working condition.
4. With PT100 sensor probe, high precision temperature measurement, small errors, high efficiency.
5. AC reducer motor, strong torsion, no noise.
6. PTFE discharge value, moveable interface, discharging completely and quickly.
7. Our company can design special kettle boday structure according to customer requirements(such as PH meter, sand core filter etc)
8. All the reaction kettle can be made of explosion-proof device according to the customer request.(The explosion-proof device refers to the ex-proof motor + ex-proof control box + ex-proof temperature field display instrument).
Why Choose Xi'an Bioland Instrument?
15+ Years of Manufacturing Excellence
For more than 15 years, we've only sold chemical process tools. Our skilled engineers understand the problems you're having with growing.
Certified Quality You Can Trust
Each unit comes with certifications from CE, ISO, UL, SGS, ATEX, and IEC. We promise that we will follow all foreign safety rules.
True Linear Scale-Up
Our product can be scaled up from the lab to production without any problems, unlike batch methods. The results of your test go straight to production without any changes to the parameters.
Explosion-Proof & Automated Control
Your workers will be safe thanks to the full explosion-proof design and possible PLC automation. Smart timing of ultrasonic control makes it easier to plan for production.
Customization Without Compromise
We offer full OEM and ODM services. In one system, you can do emulsification, decarboxylation, extraction, dispersion, catalysis, filtration, crystallization, and fractional distillation. Pick the materials, amounts of power, and process units you want to use.
Fast Delivery & Lifetime Support
Units that aren't modified take 5–7 days to ship. This can be done in 30 business days for custom setups. With every buy, you get a warranty for one year and support for life. You are kept up to date with weekly production updates that include pictures and movies.
Energy Efficiency That Saves Money
With >85% electrical-to-mechanical energy transfer, you can lower prices and boost output at the same time.
|
Model |
BL-10EX |
BL-20EX |
BL-30EX |
BL-50EX |
BL-100EX |
BL-150EX |
BL-200EX |
|
Volume(L) |
10 |
20 |
30 |
50 |
100 |
150 |
200 |
|
Power(W) |
180 |
180 |
180 |
180 |
370 |
750 |
750 |
|
Vacuum degree(Mpa) |
0.0968 |
0.0968 |
0.098 |
0.098 |
0.098 |
0.098 |
0.098 |
|
Speed(Ram) |
0~600 |
0~600 |
0~600 |
0~600 |
0~600 |
0~600 |
0~600 |
|
Stirring rod |
Stainless steel wrapped with PTFE |
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|
Thermometer |
PT100 |
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|
Ultrasonic processor system |
Can be customize as your demand 10~3000w ultrasonic power can be adjusted frequency : 19.5-20.5KHz Automatic tracking titanium alloy probe /horn: Φ40 or customzie ultrasonic process time :0 ~ 99 hours 59 minutes 59 seconds can be adjustable,: Self-diagnostic function, program automatic error correction, over-load / over- temp..etc |
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|
Voltage |
220V/50HZ or 380V |
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|
Glass material |
3.3 high borosilicate glass |
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|
Frame material |
304 stainless steel |
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|
Optional |
Heating circulator,cooling circulator,vacuum pump,metering pump,peristaltic pump,PH meter... |
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A positive displacement pump brings your feed material into the reactor. A titanium alloy sonotrode vibrates at a high frequency inside a small cylinder as the liquid passes through it.
Electrical energy is changed into mechanical movements by piezoelectric sensors. These movements make waves in the liquid that go back and forth between high and low pressure.
During rounds of low pressure, tiny bubbles of vacuum form. This rapid breakdown of these bubbles during periods of high pressure is called acoustic cavitation.
When bubbles implode, they create areas with temperatures of up to thousands of degrees and very strong compression forces. These tiny blasts separate groups of particles, damage cell walls, and speed up chemical processes.
Continuous flow ultrasonic reactor makes sure that every millilitre gets the same amount of energy, unlike batch processing where strength changes depending on how far away the probe is. This gives you consistent product quality that you can use again and again.
Jacketed cooling keeps the temperature under control. Materials that break down easily in heat, like proteins and APIs, can still be processed.
Application Fields
Pharmaceutical & Biopharmaceuticals
Produce nano-emulsions, liposomes, and API encapsulations with narrow particle size distribution. Enhance bioavailability without high-pressure homogenization wear.
Nanomaterial Preparation
Disperse carbon nanotubes, graphene, and metal nanoparticles uniformly. Eliminate agglomeration for consistent product performance.
Botanical & Herbal Extraction
Extract polyphenols, cannabinoids, and essential oils at lower temperatures. Preserve heat-sensitive bioactives while increasing yield by disrupting cell walls.
Biodiesel & Chemical Synthesis
Accelerate transesterification reactions. Reduce catalyst requirements by up to 50% and cut reaction times from hours to minutes.
Lithium Battery Slurry
Achieve uniform dispersion of electrode materials. Improve battery performance through consistent particle size and distribution.
Food & Beverage Processing
Cold pasteurization reduces microbial load without thermal damage. Create stable emulsions for dairy, sauces, and beverages.
Fine Chemical Production
Speed up sonochemistry reactions including esterification, catalysis, and polymer synthesis. Improve yield and selectivity.
Cell Disruption & Lysis
Break microbial and plant cells for protein extraction, enzyme release, and compound isolation in research and production environments.
All Xi'an Bioland Instrument reactors meet international quality standards:
Before shipping, we do a lot of tests:
Each unit goes through Factory Acceptance Testing, which is documented in photos and videos for your review.
Q: How does a product compare to high-pressure homogenizers?
Our reactor handles higher viscosities more effectively with no moving parts in the product stream. This means dramatically lower maintenance costs and zero risk of valve clogging with abrasive slurries.
Q: Can your system handle abrasive fluids?
Yes. We use hardened titanium alloys and offer ceramic-coated probes with replaceable tips. This minimizes downtime and operational expense.
Q: How do I scale up from lab to production?
Scale-up is linear. Maintain the same amplitude and specific energy input while increasing sonotrode surface area or running parallel units. Your lab results transfer accurately to production flow rates.
Q: Can you control temperature during processing?
Absolutely. Cavitation generates heat, so our industrial reactors feature jacketed flow cells for active temperature control. This prevents degradation of proteins, enzymes, and heat-sensitive APIs.
Q: What pump should I use to feed the reactor?
We recommend positive displacement pumps like progressive cavity or gear pumps. These maintain constant flow rate despite pressure fluctuations from cavitation, ensuring stable residence time and consistent treatment.
Q: Is pulse mode available?
Yes. Pulse mode alternates ultrasonic on/off cycles. This prevents deactivation of thermosensitive substances while reducing energy consumption.
Q: What's your delivery time?
Non-customized products ship in 5–7 days. Custom configurations take 30 business days with weekly progress updates.
Q: Do you provide installation support?
Yes. We offer comprehensive technical support including installation guidance, operator training, and lifetime maintenance service.
Ready to enhance your process efficiency with continuous flow ultrasonic reactor? Contact our engineering team at info@biolandequip.com for customized solutions and technical consultation.
2024-05-16
Pharmaceutical Company
The reactor is beautifully mirror-polished and fully complies with GMP requirements for the pharmaceutical industry. The performance is excellent! Overall, we are very satisfied! We also provided with some feedback on our process improvements, which we hope will be helpful.
2024-04-09
Laboratory
Excellent and professional service. Always reply our questions very fast. All reactors and chiller we received are good too.
2024-02-15
Research Institute
Quality is beyond our expectation actually. After we got the extraction equipment and started using it, the performance was beyond our expectation. Very easy to use and very efficient to run. Service always respond us very quickly. Was also very helpful to help us. Thanks Bioland team. Very happy to work with you.
2023-11-20
Biotech Company
We are happy about the new purchase as always. Equipment and services are both good.
2023-08-05
Instrument Lab
This is the second order with Bioland instrument and everything is good as the first dateText.
2023-05-12
Global Trading Partner
Bioland instrument team is very helpful and professional. The sales helped us select the right equipment for our application, and their logistics people handled the transportation and customs declaration for our shipment. All that saved us a lot of work.